N-Acetylglucosamine Functions in Cell Signaling [PDF]
Scientifica, 2012 The amino sugar N-acetylglucosamine (GlcNAc) is well known for the important structural roles that it plays at the cell surface. It is a key component of bacterial cell wall peptidoglycan, fungal cell wall chitin, and the extracellular matrix of animal ...
James B. Konopka
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N-Acetylglucosamine: Production and Applications [PDF]
Marine Drugs, 2010 N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose.
Chao-Lin Liu +2 more
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Nature Communications, 2016 Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al.
Chang Su, Yang Lu, Haoping Liu
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Conversion of N‐Acetylglucosamine to 3‐Acetamido‐5‐Acetylfuran over Al‐Exchanged Montmorillonite [PDF]
ChemistryOpen, 2023 3‐Acetamido‐5‐acetylfuran (3A5AF) is a potential platform compound for the production of nitrogen‐containing pharmaceuticals and chemicals. 3A5AF can be obtained by dehydration of chitin or its monomer, N‐acetylglucosamine (NAG).
Dr. Kiyoyuki Yamazaki +2 more
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N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens. [PDF]
PLoS Pathogens, 2015 There is growing evidence that the sugar N-acetylglucosamine (GlcNAc) plays diverse roles in cell signaling pathways that impact the virulence properties of microbes and host cells. GlcNAc is already well known as a ubiquitous structural component at the
Shamoon Naseem, James B Konopka
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Probing antibacterial drugs for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 targeting UDP-N-acetylglucosamine 1-carboxyltransferase [PDF]
Journal of Advanced Pharmaceutical Technology & Research, 2023 Fusobacterium nucleatum is a Gram-negative anaerobic bacteria that is commonly found in oral cavities and is associated with connective tissue destruction in periodontitis. UDP-N-acetylglucosamine 1-carboxyltransferase with enzyme commission number 2.5.1.
Dewi Saputri +5 more
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Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer [PDF]
Clinical and Translational MedicineBackground O‐linked N‐acetylglucosamine protein modification (O‐GlcNAcylation) is a dynamic, nutrient‐sensitive post‐translational modification frequently upregulated in cancers.
Yizhan Li +5 more
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Molecular Characterization of the N-Acetylglucosamine Catabolic Genes in Candida africana, a Natural N-Acetylglucosamine Kinase (HXK1) Mutant. [PDF]
PLoS ONE, 2016 BACKGROUND:In this study we report the genetic characterization, including expression analysis, of the genes involved in the uptake (NGT1) and catabolism (HXK1/NAG5, DAC1/NAG2, NAG1) of the aminosugar N-acetylglucosamine (GlcNAc) in Candida africana, a ...
Maria Rosa Felice +8 more
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Anomerization of N-Acetylglucosamine Glycosides Promoted by Dibromomethane and Dimethylformamide [PDF]
MoleculesIn previous quests to synthesize fragments of tumor-associated carbohydrate antigens (TACAs), we determined that bromoalkyl β glycosides of N-acetylglucosamine were labile and incompatible with some of the synthetic conditions required for the ...
Natalie B. Condino +5 more
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The Formulation of the N-Acetylglucosamine as Nanoparticles Increases Its Anti-Inflammatory Activities: An In Vitro Study [PDF]
Bioengineering, 2023 Nanomedicine can represent a new strategy to treat several types of diseases such as those with inflammatory aetiology. Through this strategy, it is possible to obtain nanoparticles with controlled shape, size, and eventually surface charge.
Alessia Mariano +3 more
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