Results 141 to 150 of about 14,921,471 (288)

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

The roles of OGT and its mechanisms in cancer

Cell & Bioscience
O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a common and important post-translational modification (PTM) linking O-linked β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues in proteins.
Xin Liu, Jing Wang, Yaoxian Xiang, Kangjie Wang, Dong Yan, Yingying Tong   +5 more
doaj   +1 more source

Sequence‐Based and Functional Analysis for the Discovery of N‐Glycan Degrading Glycosidases From the Microbial Metagenome of the Infant Gut

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This research offers valuable understanding of how N‐glycans are broken down by the gut microbiota of infants, focusing on glycoside hydrolase families GH2, GH20, and GH18. It reveals that the gut microbiota of breastfed infants has a diverse array of genes coding for these enzymes.
Irene Boscá‐Sánchez, Jesús Rodríguez‐Díaz, María J. Yebra   +2 more
wiley   +1 more source

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano, Carmen Marino, Manuela Grimaldi, Michela Buonocore, Angelo Santoro, Anna Maria D'Ursi   +5 more
wiley   +1 more source

Electroactive Biodegradable Nerve Conduits Based on Alginate–Gelatine Polymer Matrix Modified With Inorganic Nanoparticles

Natural Sciences, Volume 6, Issue 2, April 2026.
The effects of ZnO, fullerene C60 and polyaniline (PANI) nanoparticles in hybrid nerve conduits are explored. The composites show enhanced electrical conductivity, permeability to physiological fluids and mechanical stability. The biocompatibility of composites is confirmed by in vivo and in vitro studies.
Liudmyla Sukhodub, Mariia Kumeda, Oleksandr Tsyndrenko, Natalia Bozhko, Liudmyla Vovchenko, Volodymyr Prokopiuk, Oleksander Petrenko, Leonid Sukhodub   +7 more
wiley   +1 more source

Potential of bacteria isolated from chitin‐enriched soil against Euschistus heros (Hemiptera: Pentatomidae)

Pest Management Science, Volume 82, Issue 4, Page 3552-3561, April 2026.
B. thuringiensis and B. altitudinis, isolated from chitin‐enriched soil, causing mortality in Euchistus heros under laboratory conditions. First report of B. altitudinis in the control of E. heros. Abstract BACKGROUND Biological control using entomopathogenic microorganisms is a more sustainable alternative to chemical pesticides for managing insect ...
Vicente Guilherme Handte, Valéria Ortaça Portela, Nariane de Andrade, Valdemir Bittencourt Soares, Andressa de Souza Pollo, Ricardo Antonio Polanczyk, Rodrigo Josemar Seminoti Jacques   +6 more
wiley   +1 more source

Characterization of GDP-mannose Pyrophosphorylase from Escherichia Coli O157:H7 EDL933 and Its Broad Substrate Specificity

, 2005
GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol, Kang, Young Bok (Abraham), Kim, Byung-Gee, Lee, Kwang-Won, Lee, Tek-Hyung, Park, Sung-Soo, Yang, Yung-Hun   +6 more
core  

Towards a Novel Biocontrol Strategy: High Performance of Optimised Cell Wall‐Degrading Enzymes Secreted by Escovopsis primorosea LBM 277

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Escovopsis primorosea LBM 277 efficiently produced proteases, β‐1,3‐glucanases and chitinases under submerged fermentation using Leucoagaricus gongylophorus cell walls and Mandels complex. RSM‐BBD optimization significantly increased enzyme activity. The enzymatic cocktail remained stable for 30 days at room temperature and pH 4–6, aligning with the ...
Marcela Paola Barengo, Natalia Soledad Amerio, Gustavo Ángel Bich, Pedro Darío Zapata, María Lorena Castrillo   +4 more
wiley   +1 more source

An N-acetylglucosamine transporter required for arbuscular mycorrhizal symbioses in rice and maize

Nature Plants, 2017
Marina Nadal, R. Sawers, Shamoon Naseem, B. Bassin, Corinna A. Kulicke, A. Sharman, G. An, Kyungsook An, K. Ahern, Amanda Romag, T. Brutnell, C. Gutjahr, N. Geldner, C. Roux, E. Martinoia, J. Konopka, U. Paszkowski   +16 more
semanticscholar   +1 more source

Rhizobacteria Exopolysaccharide: A Boon in Reclaiming Soil Fertility, Augmenting Plant Growth and Plant Stress Resilience

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Microbial exopolysaccharides (EPS) enhance plant stress tolerance and soil health by improving water retention, nutrient cycling, and resilience to salinity and heavy metals, offering a biodegradable and eco‐friendly alternative to synthetic polymers for sustainable agriculture. ABSTRACT Microbial exopolysaccharides (EPSs) serve multiple industrial and
Aishmita Gantait, Sam A. Masih, Ann Maxton, Adriano Sofo, Rosangela Addesso   +4 more
wiley   +1 more source