Results 41 to 50 of about 13,016,842 (92)
Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
The Lancet, 2020 Summary Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are ...Christopher J L Aleksandr Y Peng Cristiana Kaja M Mohsen Foad Murray Aravkin Zheng Abbafati Abbas Abbasi-Kangeva, C. Murray, A. Aravkin, P. Zheng, C. Abbafati, K. Abbas, M. Abbasi-Kangevari, F. Abd-Allah, A. Abdelalim, M. Abdollahi, Ibrahim Abdollahpour, Kedir Hussein Abegaz, Hassan Abolhassani, Victor Aboyans, Lucas Guimarães Abreu, Michael R. M. Abrigo, Ahmed Abualhasan, L. Abu-Raddad, A. Abushouk, M. Adabi, Victor Adekanmbi, A. Adeoye, O. Adetokunboh, Davoud Adham, S. Advani, Gina Agarwal, S. K. Aghamir, Anurag Agrawal, Tauseef Ahmad, K. Ahmadi, Mehdi Ahmadi, H. Ahmadieh, M. Ahmed, T. Akalu, R. Akinyemi, T. Akinyemiju, B. Akombi, C. Akunna, Fares Alahdab, Z. Al-Aly, K. Alam, Samiah Alam, Tahiya Alam, Fahad Mashhour Alanezi, Turki M. Alanzi, B. Alemu, K. Alhabib, Muhammad Ali, Saqib Ali, G. Alicandro, C. Alinia, V. Alipour, H. Alizade, S. Aljunid, François Alla, Peter Allebeck, A. Almasi-Hashiani, Hesham M Al-Mekhlafi, Jordi Alonso, K. Altirkawi, Mostafa Amini-Rarani, Fatemeh Amiri, D. Amugsi, R. Ancuceanu, Deanna Anderlini, Jason A Anderson, C. Andrei, Tudorel Andrei, Colin Angus, Mina Anjomshoa, F. Ansari, Alireza Ansari-Moghaddam, I. Antonazzo, C. Antonio, Catherine M. Antony, E. Antriyandarti, Davood Anvari, R. Anwer, Seth Christopher Yaw Appiah, J. Arabloo, M. Arab-Zozani, F. Ariani, Bahram Armoon, J. Ärnlöv, A. Arzani, Mehran Asadi-Aliabadi, A. Asadi-Pooya, Charlie Ashbaugh, Michael Assmus, Z. Atafar, Desta Debalkie Atnafu, Maha Moh’d Wahbi Atout, F. Ausloos, M. Ausloos, B. P. Ayala Quintanilla, Getinet Ayano, M. Ayanore, S. Azari, G. Azarian, Z. N. Azene, A. Badawi, A. Badiye, M. Bahrami, M. Bakhshaei, A. Bakhtiari, Shankar M. Bakkannavar, Alberto Baldasseroni, Kylie Ball, S. Ballew, Daniela Balzi, Maciej Banach, Srikanta K Banerjee, Agegnehu Bante, A. G. Baraki, S. Barker-Collo, T. Bärnighausen, L. Barrero, Celine M Barthelemy, Lingkan Barua, Sanjay Basu, B. Baune, M. Bayati, Jacob S. Becker, Neeraj Bedi, Ettore Beghi, Y. Béjot, M. L. Bell, F. Bennitt, I. Benseñor, Kidanemaryam Berhe, Adam E. Berman, A. Bhagavathula, R. Bhageerathy, N. Bhala, Dinesh Bhandari, Krittika Bhattacharyya, Z. Bhutta, A. Bijani, B. Bikbov, M. B. Bin Sayeed, A. Biondi, Binyam Minuye Birihane, C. Bisignano, R. Biswas, Helen Bitew, S. Bohlouli, Mehdi Bohluli, Alexandra S. Boon-Dooley, Guilherme Borges, A. Borzì, S. Borzouei, C. Bosetti, S. Boufous, D. Braithwaite, N. Breitborde, S. Breitner, H. Brenner, P. Briant, A. Briko, N. Briko, Gabrielle Britton, Dana Bryazka, Blair R Bumgarner, K. Burkart, R. Burnett, Sharath Burugina Nagaraja, Z. Butt, F. L. Caetano dos Santos, Leah E Cahill, L. 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Karim, G. Kassa, S. Katikireddi, G. Kayode, Ali Kazemi Karyani, P. Keiyoro, Cathleen Keller, L. Kemmer, Parkes Kendrick, Nauman Khalid, M. Khammarnia, E. Khan, Maseer Khan, Khaled Khatab, M. Khater, M. Khatib, M. Khayamzadeh, Salman Khazaei, C. Kieling, Y. Kim, R. Kimokoti, A. Kisa, S. Kisa, Mika Kivimäki, Luke D. Knibbs, A. Knudsen, Jonathan M Kocarnik, S. Kochhar, Jacek A. Kopec, V. A. Korshunov, P. Koul, Ai Koyanagi, Moritz U. G. Kraemer, K. Krishan, Kristopher J. Krohn, H. Kromhout, Barthelemy Kuate Defo, G. Kumar, Vivek Kumar, O. Kurmi, Dian Kusuma, C. La Vecchia, Ben Lacey, D. Lal, R. Lalloo, T. Lallukka, Faris Lami, I. Landires, Justin J. Lang, S. Langan, Anders O. Larsson, Savita Lasrado, P. Lauriola, J. Lazarus, P. H. Lee, Shaun Wen Huey Lee, K. E. LeGrand, J. Leigh, Matilde Leonardi, H. Lescinsky, Janni Leung, Miriam Levi, Shanshan Li, Lee-Ling Lim, S. Linn, Shiwei Liu, Simin Liu +499 moresemanticscholar +1 more sourceLarge-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Nature Genetics, 2012 To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent.Andrew P Benjamin F Tanya M Teresa Ayellet V Valgerdur Ro Morris Voight Teslovich Ferreira Segrè Steinthorsd, Andrew P. Morris, B. Voight, Tanya M. Teslovich, T. Ferreira, A. Segrè, V. Steinthorsdottir, R. Strawbridge, H. Khan, H. Grallert, A. Mahajan, I. Prokopenko, H. Kang, C. Dina, T. Esko, Ross M. Fraser, S. Kanoni, Ashish Kumar, V. Lagou, C. Langenberg, J. Luan, C. Lindgren, M. Müller-Nurasyid, S. Pechlivanis, N. W. Rayner, L. Scott, S. Wiltshire, L. Yengo, L. Kinnunen, E. Rossin, S. Raychaudhuri, Andrew D. Johnson, A. Dimas, R. Loos, S. Vedantam, Han Chen, J. Florez, C. Fox, Ching‐Ti Liu, Denis Rybin, D. Couper, W. Kao, Man Li, M. Cornelis, P. Kraft, Qi Sun, R. V. van Dam, H. Stringham, P. Chines, K. Fischer, P. Fontanillas, O. Holmen, S. Hunt, A. Jackson, A. Kong, R. Lawrence, Julia Meyer, J. Perry, Carl G. P. Platou, Simon C. Potter, E. Rehnberg, N. Robertson, S. Sivapalaratnam, A. Stančáková, K. Stirrups, G. Thorleifsson, E. Tikkanen, A. Wood, P. Almgren, M. Atalay, R. Benediktsson, L. Bonnycastle, N. Burtt, Jason P. Carey, G. Charpentier, A. Crenshaw, A. Doney, M. Dorkhan, S. Edkins, V. Emilsson, Elodie Eury, T. Forsén, K. Gertow, B. Gigante, George B. Grant, C. Groves, C. Guiducci, C. Herder, Á. Hreidarsson, J. Hui, A. James, A. Jonsson, W. Rathmann, N. Klopp, J. Kravic, K. Krjutškov, C. Langford, K. Leander, E. Lindholm, S. Lobbens, S. Männistö, G. Mirza, Thomas W. Mühleisen, B. Musk, Melissa Parkin, L. Rallidis, J. Saramies, B. Sennblad, Sonia H. Shah, G. Sigurðsson, A. Silveira, G. Steinbach, B. Thorand, J. Trakalo, F. Veglia, R. Wennauer, W. Winckler, D. Zabaneh, H. Campbell, C. V. van Duijn, A. Uitterlinden, A. Hofman, E. Sijbrands, G. Abecasis, K. Owen, E. Zeggini, M. Trip, N. Forouhi, A. Syvänen, J. Eriksson, L. Peltonen, M. Nöthen, B. Balkau, C. Palmer, V. Lyssenko, T. Tuomi, B. Isomaa, D. Hunter, L. Qi, A. Shuldiner, M. Roden, I. Barroso, T. Wilsgaard, J. Beilby, K. Hovingh, J. Price, James F. Wilson, R. Rauramaa, T. Lakka, L. Lind, G. Dedoussis, I. Njølstad, N. Pedersen, K. Khaw, N. Wareham, S. Keinanen-Kiukaanniemi, T. Saaristo, E. Korpi-Hyövälti, J. Saltevo, M. Laakso, J. Kuusisto, A. Metspalu, F. Collins, K. Mohlke, R. Bergman, J. Tuomilehto, B. Boehm, C. Gieger, K. Hveem, S. Cauchi, P. Froguel, D. Baldassarre, E. Tremoli, S. Humphries, D. Saleheen, J. Danesh, E. Ingelsson, S. Ripatti, V. Salomaa, R. Erbel, K. Jöckel, S. Moebus, A. Peters, T. Illig, U. de Faire, A. Hamsten, A. D. Morris, P. Donnelly, T. Frayling, A. Hattersley, E. Boerwinkle, O. Melander, S. Kathiresan, P. Nilsson, P. Deloukas, U. Thorsteinsdóttir, L. Groop, K. Stefánsson, F. Hu, J. Pankow, J. Dupuis, J. Meigs, D. Altshuler, M. Boehnke, M. McCarthy +204 moresemanticscholar +1 more sourceGlobal, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
The Lancet, 2016 Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease.M. Forouzanfar, A. Afshin, Lily T Alexander, H. R. Anderson, Z. Bhutta, S. Biryukov, M. Brauer, R. Burnett, Kelly M. Cercy, F. Charlson, A. Cohen, L. Dandona, Kara Estep, A. Ferrari, J. Frostad, N. Fullman, P. Gething, W. Godwin, Max G Griswold, Simon Iain Hay, Y. Kinfu, H. Kyu, H. Larson, Xiaofeng Liang, Stephen S. Lim, Patrick Y. Liu, Alan D. Lopez, R. Lozano, L. Marczak, G. Mensah, A. Mokdad, M. Moradi-Lakeh, M. Naghavi, B. Neal, M. Reitsma, Gregory A. Roth, J. Salomon, P. Sur, T. Vos, Joseph A Wagner, Haidong Wang, Yi Zhao, Maigeng Zhou, Gunn Marit Aasvang, A. Abajobir, K. H. Abate, C. Abbafati, K. Abbas, F. Abd-Allah, A. Abdulle, S. Abera, Biju Abraham, L. Abu-Raddad, G. Abyu, A. Adebiyi, I. Adedeji, Z. Ademi, A. K. Adou, J. Adsuar, E. Agardh, A. 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Olsen, B. Olusanya, J. Olusanya, John Nelson Opio, Eyal Oren, R. Orozco, Alberto Ortiz, E. Ota, Mahesh Pa, A. Pana, Eun‐Kee Park, C. Parry, M. Parsaeian, Tejas Patel, A. P. Caicedo, Snehal T. Patil, S. Patten, G. Patton, N. Pearce, David M Pereira, N. Perico, K. Pesudovs, M. Petzold, M. Phillips, F. Piel, J. Pillay, D. Plass, S. Polinder, C. Pond, C. Pope, D. Pope, S. Popova, R. Poulton, F. Pourmalek, N. Prasad, M. Qorbani, Rynaz Rabiee, A. Radfar, Anwar Rafay, V. Rahimi-Movaghar, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, S. Rahman, R. Rai, Sasa Rajsic, M. Raju, U. Ram, S. Rana, K. Ranganathan, P. Rao, Christian García, A. Refaat, C. Rehm, J. Rehm, Nikolas Reinig, G. Remuzzi, S. Resnikoff, A. Ribeiro, J. Rivera, H. S. Roba, Alina Rodriguez, S. Rodríguez-Ramírez, D. Rojas-Rueda +499 moresemanticscholar +1 more sourceDiagnosing COVID-19: The Disease and Tools for Detection
ACS Nano, 2020 COVID-19 has spread globally since its discovery in Hubei province, China in December 2019. A combination of computed tomography imaging, whole genome sequencing, and electron microscopy were initially used to screen and identify SARS-CoV-2, the viral ...Buddhisha N Udugama, Pranav Kadhiresan, Hannah N. Kozlowski, Ayden Malekjahani, M. Osborne, Vanessa Y. C. Li, Hongmin Chen, S. Mubareka, J. Gubbay, W. Chan +9 moresemanticscholar +1 more sourceResolving the fibrotic niche of human liver cirrhosis at single cell level
Nature, 2019 Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available.P. Ramachandran, R. Dobie, J. Wilson-Kanamori, Elena Dorà, Beth E. P. Henderson, N. T. Luu, N. T. Luu, J. R. Portman, Kylie P. Matchett, M. Brice, John A. Marwick, R. S. Taylor, M. Efremova, R. Vento-Tormo, N. Carragher, T. Kendall, J. Fallowfield, E. Harrison, D. Mole, D. Mole, S. Wigmore, S. Wigmore, Phil N. Newsome, Phil N. Newsome, C. Weston, C. Weston, J. Iredale, Frank Tacke, J. Pollard, J. Pollard, C. Ponting, J. Marioni, J. Marioni, S. Teichmann, Sarah A. Teichmann, N. Henderson +35 moresemanticscholar +1 more sourceIntegrated genomic characterization of oesophageal carcinoma
Nature, 2017 Oesophageal cancers are prominent worldwide; however, there are few targeted therapies and survival rates for these cancers remain dismal. Here we performed a comprehensive molecular analysis of 164 carcinomas of the oesophagus derived from Western and ...Jihun Reanne Andrew J. A. Gordon Robert D. Andrew D. Jul Kim Bowlby Mungall Robertson Odze Cherniack Shih P, Jihun Kim, Reanne Andrew J. A. Gordon Bowlby Mungall Robertson, R. Bowlby, A. Mungall, A. G. Robertson, R. Odze, Andrew D. Juliann Chandra Sekhar Carrie Andrew Samuel R. Cherniack Shih Pedamallu Cibulskis Dunford Meier K, A. Cherniack, J. Shih, C. Pedamallu, C. Cibulskis, Andrew J. Dunford, S. Meier, Jaegil Kim, Benjamin J. Hsin-Ta Alexandra M. Raphael Wu Wong, Benjamin J. Raphael, Hsin-Ta Wu, Alexandra M. Wong, J. Willis, Adam J. Sarah Bass Derks, A. Bass, S. Derks, Katherine Shannon J. Garman McCall, Katherine S. Garman, S. McCall, M. Wiznerowicz, Angeliki Michael Pantazi Parfenov, A. 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