Results 201 to 210 of about 976,099 (318)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The Impact of Exercise Interventions on the Network Structure of Psychotic Symptoms: Analysis From Two Clinical Trials. [PDF]

Early Interv Psychiatry
Laurendeau K, Bernard P, Piché F, Abdel-Baki A, Romain AJ.   +4 more
europepmc   +1 more source

On equicontinuous factors of flows on locally path-connected compact\n spaces [PDF]

, 2019
Nikolai Edeko
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Needle Cricothyrotomy Connection Options Provide Similar Oxygen Flow Rates. [PDF]

Cureus
Oberhauser-Lim N, Morales EA, Rotinsulu AG, Torres AN, Young TP.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Three-Dimensional Reconstruction and Scour Volume Detection of Offshore Wind Turbine Foundations Based on Side-Scan Sonar. [PDF]

Sensors (Basel)
Wang Y, Tao L, Yuan M, Yang J.
europepmc   +1 more source

Level sets on uniform quotient mappings from $R^n$ to R do not need to be locallaly connected

, 2004
Beata Randrianantoanina
openalex   +1 more source

Improved approximation algorithms for $k$-connected $m$-dominating set\n problems [PDF]

, 2017
Zeev Nutov
openalex   +1 more source