Results 51 to 60 of about 6,740 (213)

Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction

open access: yesFrontiers in Toxicology, 2022
Cytochrome P450 (CYP) enzymes play a key role in the metabolism of both xenobiotics and endogenous chemicals, and the activity of some CYP isoforms are susceptible to induction and/or inhibition by certain chemicals. As CYP induction/inhibition can bring
Miriam Naomi Jacobs   +2 more
doaj   +1 more source

In Vivo Effects of N,N‐Diethyl‐Meta‐Toluamide (DEET) Exposure on Sinonasal Epithelia in a Murine Model

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Environmental factors, including airborne toxicants, are thought to contribute to the pathogenesis of chronic rhinosinusitis, although the exact mechanism is not fully understood. The purpose of this pilot study is to assess the impact of pesticide, N,N‐diethyl‐meta‐toluamide (DEET), on the sinonasal epithelium using an in vivo murine model ...
Jivianne T. Lee   +4 more
wiley   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

open access: yesJournal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac   +15 more
wiley   +1 more source

Fingerprinting groundwater pollution in catchments with contrasting contaminant sources using microorganic compounds [PDF]

open access: yes, 2013
Evaluating the occurrence of microorganics helps to understand sources and processes which may be controlling the transport and fate of emerging contaminants (ECs).
Edwards, Laura   +3 more
core   +1 more source

Structure‐Based Screening of Amides with Potential to Overcome Aedes aegypti Insecticide Resistance

open access: yesChemistrySelect, Volume 10, Issue 35, September 16, 2025.
Given the great insecticidal potential of compounds containing the amide function, the present study applied the structure‐based virtual screening (SBVS) strategy through docking and molecular dynamics to screen more than 27,000 amides from a ChemBL library and identify potential inhibitors of important Aedes aegypti enzymes that can overcome ...
Érick Caique Santos Costa   +10 more
wiley   +1 more source

Unveiling the potential health risks induced by photolysis of insect repellents DEET under simulated sunlight

open access: yesWater Cycle
N, N-diethyl-m-toluamide (DEET) is a widely used active ingredient in insect repellents, particularly in areas where mosquitoes are prevalent. Although the photolysis of DEET is inevitably to occur when exposed to sunlight, the potential risks associated
Xin-Yi Jiao   +11 more
doaj   +1 more source

Synergistic Cytotoxicity of Permethrin and N,N‐Diethyl‐Meta‐Toluamide on Sinonasal Epithelial Cells

open access: yesOTO Open, Volume 9, Issue 3, July-September 2025.
Abstract N,N‐Diethyl‐meta‐toluamide (DEET) and permethrin are pesticides commonly used in combination due to their synergistic insecticidal and repellent properties. This study investigates whether simultaneous exposure to these compounds elicits synergistic cytotoxicity in sinonasal epithelial cells (SNECs).
Jivianne T. Lee   +7 more
wiley   +1 more source

The ovipositor cue indole inhibits animal host attraction in Aedes aegypti (Diptera: Culicidae) mosquitoes

open access: yesParasites & Vectors, 2022
Background Mosquitoes are responsible for disease transmission worldwide. They possess the ability to discriminate between different ecological resources, including nectar sources, animal hosts and oviposition sites, a feature mediated by their olfactory
Amir Dekel   +4 more
doaj   +1 more source

In vitro testing of alternative synthetic and natural antiparasitic compounds against the monogenean sparicotyle chrysophrii [PDF]

open access: yes, 2021
Gill monogenean Sparicotyle chrysophrii is considered the most detrimental fish parasite to the Mediterranean aquaculture. Treatment of sparicotylosis relies on frequent gill inspections correlated with the seasonal increase in seawater temperature ...
Manuguerra S.   +7 more
core   +1 more source

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