Results 111 to 120 of about 22,757,743 (311)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EPJ Web of Conferences, 2010 An experimental set-up designed to investigate the origin of the prompt scission neutrons in fission processes by using an array neutron detector is modeled.
Petrascu H. +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Orthogonal least squares algorithm for training multi-output radial basis function networks
, 1992 A constructive learning algorithm for multioutput radial basis function networks is presented. Unlike most network learning algorithms, which require a fixed network structure, this algorithm automatically determines an adequate radial basis function ...
Cowan, C. F. N., Grant, P. M., Chen, S.
core
, 2023 Gandhi Fernando Pavón-Romero,1 Ramcés Falfán-Valencia,2 Katia Vanessa Gutiérrez-Quiroz,1 Estivaliz Arizel De La O-Espinoza,1 Nancy Haydée Serrano-Pérez,1 Fernando Ramírez-Jiménez,1 Luis M Teran1 1Department of Immunogenetics and Allergy, Instituto ...
Falfán-Valencia R +6 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A note on the $\Sopfr(n)$ function
, 2011 The $\Sopfr(n)$ function is defined as the sum of prime factors of $n$ each of which is taken with its multiplicity. This function is studied numerically. The analogy between $\Sopfr(n)$ and the primes distribution function is drawn and some conjectures for prime numbers formulated in terms of the $\Sopfr(n)$ function are suggested.
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source