Results 11 to 20 of about 85,046 (159)
Frontiers in Immunology, 2021 Background recently, many researches have concentrated on the relevance between N1-methyladenosine (m1A) methylation modifications and tumor progression and prognosis. However, it remains unknown whether m1A modification has an effect in the prognosis of
Jinhui Liu +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Neutrophils have been classically viewed as a homogenous population. Recently, neutrophils were phenotypically classified into pro-inflammatory N1 and anti-inflammatory N2 sub-populations, but the functional differences between the two subtypes are not ...
A. Mihaila +14 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 RNA methylation is considered a significant epigenetic modification, a process that does not alter gene sequence but may play a necessary role in multiple biological processes, such as gene expression, genome editing, and cellular differentiation.
Yating Xu +6 more
semanticscholar +1 more source
METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth
Protein & Cell, 2021 Histidine methylation has been known for many years (Searle and Westall, 1951), but only a few proteins carrying such modifications have been studied (Webb et al., 2010; AlHadid et al., 2014; Kwiatkowski et al., 2018; Guo et al., 2019; Wilkinson et al ...
Mengyue Lv +13 more
semanticscholar +1 more source
N1-acetylspermidine is a determinant of hair follicle stem cell fate
Journal of Cell Science, 2021 Stem cell differentiation is accompanied by increased mRNA translation. The rate of protein biosynthesis is influenced by the polyamines putrescine, spermidine and spermine, which are essential for cell growth and stem cell maintenance. However, the role
K. Allmeroth +11 more
semanticscholar +1 more source
An Attempt to Polarize Human Neutrophils Toward N1 and N2 Phenotypes in vitro
Frontiers in Immunology, 2020 Neutrophils act as the first line of defense against invading pathogens. Although traditionally considered in context of their antimicrobial effector functions, the importance of tumor-associated neutrophils (TANs) in the development of cancer has become
Mareike Ohms, Sonja Möller, T. Laskay
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Intronic splicing silencer N1 (ISS-N1) located within Survival Motor Neuron 2 (SMN2) intron 7 is the target of a therapeutic antisense oligonucleotide (ASO), nusinersen (Spinraza), which is currently being used for the treatment of spinal muscular ...
E. Ottesen, Diou Luo, N. Singh, R. Singh
semanticscholar +1 more source
Journal of Clinical Oncology, 2020 PURPOSE ADJUVANT-CTONG1104 (ClinicalTrials.gov identifier: NCT01405079), a randomized phase III trial, showed that adjuvant gefitinib treatment significantly improved disease-free survival (DFS) versus vinorelbine plus cisplatin (VP) in patients with ...
Wenhui Zhong +28 more
semanticscholar +1 more source
Advances in Operations Research, Volume 2012, Issue 1, 2012., 2012 The problems studied are the separable variational inequalities with linearly coupling constraints. Some existing decomposition methods are very problem specific, and the computation load is quite costly. Combining the ideas of proximal point algorithm (PPA) and augmented Lagrangian method (ALM), we propose an asymmetric proximal decomposition method ...
Xiaoling Fu +4 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2012, Issue 1, 2012., 2012 Chlorella sorokiniana (CS) is a unicellular green alga. The extracts of Chlorella have been used as treatments for relieving hypertension and modulating immune response. The detailed mechanisms are not clear yet. In this study, we sought to study the molecular mechanisms for the polysaccharide fraction of CS‐induced immune response. We pulsed dendritic
Nien-Tzu Chou +7 more
wiley +1 more source