Results 1 to 10 of about 1,309 (171)

Chemoorganoautotrophic lifestyle of the anaerobic enrichment culture N47 growing on naphthalene [PDF]

open access: yesCommunications Biology
In almost all respiratory organisms, organic substrates are degraded via catabolic processes to the central metabolite acetyl-CoA which is then oxidized to CO2 for energy metabolism or used as a building block for anabolism.
Lisa Voskuhl   +2 more
exaly   +3 more sources

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection. [PDF]

open access: yesAdv Sci (Weinh)
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Wang Z   +8 more
europepmc   +2 more sources

When Bigger is Better: Lanthanum Complexes of Bis(phenoxy-amidine) FAlen Ligands as Unique Catalysts for the Isoselective Ring-Opening Polymerization of Racemic β-Lactones. [PDF]

open access: yesAngew Chem Int Ed Engl
Discrete lanthanum complexes supported by new bis(phenoxy‐amidine) ligands act as highly efficient ring‐opening polymerization (ROP) catalysts of simple and functional β‐propiolactones rac‐BLR under mild conditions, returning in a controlled manner the corresponding linear polymers PBLR with high isoselectivity, no matter the nature and polarity of the
Bui TT   +7 more
europepmc   +3 more sources

Elucidation of Proteoforms of Chinese Hamster Ovary (CHO) Phospholipase B-Like 2 (PLBL2) Captured From a Monoclonal Antibody. [PDF]

open access: yesBiotechnol Bioeng
A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Dolan ME   +6 more
europepmc   +2 more sources

Glycosylation signature of plasma IgA of critically ill COVID-19 patients [PDF]

open access: yesFrontiers in Immunology
Thromboembolic complications are common in severe COVID-19 and are thought to result from excessive neutrophil-extracellular-trap (NET)-driven immunothrombosis.
Daniel P. Potaczek   +22 more
doaj   +2 more sources

Effect of live-high, train-low strategy induced by chronic low-dose carbon monoxide exposure on haematological parameters and performance in trained individuals. [PDF]

open access: yesExp Physiol
Abstract Altitude training enhances haematological adaptations and endurance at sea level, typically requiring exposure to ∼2500 m altitude for 3–4 weeks. Emerging evidence suggests that low‐dose carbon monoxide (CO) inhalation might mimic hypoxia and might be used by elite athletes.
Villanova S   +3 more
europepmc   +2 more sources

Machine learning driven design and optimization of a compact dual Port CPW fed UWB MIMO antenna for wireless communication [PDF]

open access: yesScientific Reports
In this article, a compact dual port Multiple Input Multiple Output (MIMO) Coplanar Waveguide (CPW) fed Ultra-Wideband (UWB) antenna for the next generation wireless communication using Machine Learning (ML) optimization is presented.
Jayant Kumar Rai   +7 more
doaj   +2 more sources

Design of MIMO antenna for 6G applications supported by fractal geometry [PDF]

open access: yesScientific Reports
In this paper, a microstrip patch antenna is designed and proposed in a 2 × 2 MIMO configuration for use in 6G wireless communications in upper mid-band like 7.125–8.4 GHz.
Ashwini Kumar   +5 more
doaj   +2 more sources

Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma [PDF]

open access: yesInternational Journal of Oral Science
Dysregulated Epiregulin (EREG) can activate epidermal growth factor receptor (EGFR) and promote tumor progression in head and neck squamous cell carcinoma (HNSCC). However, the mechanisms underlying EREG dysregulation remain largely unknown.
Shengming Xu   +11 more
doaj   +2 more sources

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