Results 131 to 140 of about 2,965,078 (287)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 1997 v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through a grant from the Stony Brook Alumni ...
Stony Brook University Statesman
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 2009 v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through a grant from the Stony Brook Alumni ...
Stony Brook University Statesman
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ingeniería Mecánica, 2002 En este trabajo se utiliza el Método de los Elementos Finitos para estudiar la combinación de diferentes parámetros, y suinfluencia en la vida útil de la prótesis total de cadera utilizando como criterio la falla del cemento que une estas prótesis ...
G. García del pino +2 more
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, 1973 v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through a grant from the Stony Brook Alumni ...
Stony Brook University Statesman
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Expediente - Horizonte, Belo Horizonte, v. 17, n. 53, maio-ago. 2019
Horizonte, 2019 Expediente - Horizonte, Belo Horizonte, v. 17, n.
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