Results 191 to 200 of about 2,970,625 (288)

Characteristics, management, and outcomes of patients with VIPoma-A retrospective analysis of the ENETS database. [PDF]

J Neuroendocrinol
Bartsch DK, Mais L, de Mestier L, Baudin E, Kaltsas G, Hofland J, Garcia-Carbonero R, Tiensuu Janson E, McNamara MG, Andreassen M, Grozinsky-Glasberg S, Spada F, Leupe H, Panzuto F, Fleschen M, Klinkhammer H.   +15 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A WATERSPOUT IN LATITUDE 53° N

Monthly Weather Review, 1925
openaire   +1 more source

Acceptance and preferences for different nicotine substitute products to reduce tobacco smoking in people living with HIV: Results from an internal pilot study of a randomized trial. [PDF]

Tob Induc Dis
Schönenberger CM, Ochoa SC, Speich B, Haerry DH, Cart-Richter E, Jackson-Perry D, Hutter A, Panettieri L, Aggeler S, Chaudron SE, Calmy A, Cavassini M, Abela IA, Kusejko K, Günthard HF, Nemeth J, Rauch A, Wandeler G, Schmid P, Dörr T, Surial B, Berthet A, Auer R, Stoeckle MP, Labhardt N, Chammartin F, Briel M, Amstutz A.   +27 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effect of a Mobile App on Medication Errors During Simulated Pediatric Cardiopulmonary Resuscitation: PEDIDOSIS App vs. Conventional Methods. A Multicenter Simulation-based Randomized Controlled Trial. [PDF]

J Med Syst
Martínez-Serrano A, Ruiz-Rojo H, Ruano Encinar M, García-Sánchez P, Durantez-Fernández C, de Rojas T.   +5 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Safety and effectiveness of nonoperative management in liver lacerations: a retrospective cohort study. [PDF]

Ulus Travma Acil Cerrahi Derg
Değirmencioğlu G, Kütük D, Çanakcı MH, Yıldırım M, Kurt MH.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cahier d'Histoire Immédiate n° 53

, 2020
openaire   +2 more sources