Results 201 to 210 of about 26,004 (264)

Neoadjuvant tislelizumab plus nab-paclitaxel and carboplatin for triple-negative breast cancer: a multicenter, open-label, phase II cTRIO study. [PDF]

EClinicalMedicine
Wang F, Hao X, Geng C, Lin Y, Liu Z, Fu P, Liu Q, Yu Z, Jiang Z.   +8 more
europepmc   +1 more source

Atezolizumab + Chemotherapy for Advanced Non‐Small Cell Lung Cancer in Japanese Clinical Practice (J‐TAIL‐2)

Cancer Science, Volume 117, Issue 3, Page 727-738, March 2026.
The J‐TAIL‐2 prospective, observational study evaluated atezolizumab combined with several chemotherapy regimens in patients with advanced/metastatic non‐small cell lung cancer in routine clinical practice in Japan. The real‐world efficacy and safety of each atezolizumab combination were found to be comparable to those seen in the relevant global ...
Hiroshige Yoshioka, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Junichi Shimizu, Eisaku Miyauchi, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Akito Hata, Akira Kisohara, Shoichi Kuyama, Masafumi Yamaguchi, Asako Miwa, Shunichiro Iwasawa, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

Efficacy and safety of the S-1, nab-paclitaxel, and gemcitabine triplet regimen in patients with resected pancreatic ductal adenocarcinoma. [PDF]

Front Oncol
Ran D, Geng C, Cha Z, Nie X, Atigu A, Zhao C, Xu X.   +6 more
europepmc   +1 more source

Targeting SPP1‐CD44‐Hedgehog Axis Elicits Therapeutic Effects in Hepatocellular Carcinoma by Suppressing Intratumoral Fibrosis

Cancer Science, Volume 117, Issue 3, Page 670-682, March 2026.
SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara, Shu Shimada, Yoshimitsu Akiyama, Megumi Hatano, Yusuke Chino, Suguru Miyazawa, Hanako Tamura, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Shuichi Watanabe, Eriko Katsuta, Keiichi Akahoshi, Kenichi Ohashi, Minoru Tanabe, Daisuke Ban, Shinji Tanaka   +16 more
wiley   +1 more source

Solvent-based or nab-paclitaxel plus ramucirumab for pretreated gastric cancer with peritoneal dissemination and prespecified biomarker analysis (P-SELECT/WJOG10617G): a randomised phase 2 trial in Japan. [PDF]

EClinicalMedicine
Hirata K, Hamamoto Y, Shoji H, Hara H, Kondoh C, Yasui H, Kajiwara T, Baba E, Ando T, Sugimoto N, Kawakami H, Katsuya H, Nagase M, Yamamoto Y, Yoshimura K, Ando M, Imamura CK, Yamazaki K, Hironaka S, Muro K.   +19 more
europepmc   +1 more source

SUSD2 Promotes Metastasis and Primary Tumor Growth in Pancreatic Cancer Cells via Integrin–FAK Signaling Activation

Cancer Science, Volume 117, Issue 3, Page 711-726, March 2026.
This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida, Tomokazu Ohishi, Isao Momose, Shun‐ichi Ohba, Kyohei Kurosawa, Akiko Harakawa, Hiroyuki Inoue, Minori Senoo, Daisuke Tatsuda, Hikaru Abe, Atsushi Masamune, Manabu Kawada   +11 more
wiley   +1 more source

Pneumocystis Pneumonia in a Patient Receiving Nab-paclitaxel Plus Gemcitabine for Unresectable Pancreatic Cancer. [PDF]

Intern Med
Takano A, Himeji D, Shiiba R, Kushima N, Kinoshita E, Kamiike R, Tanaka GI, Arita S.   +7 more
europepmc   +1 more source

Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning, Balagopal Pai, Maike Collienne, Isabel Ben‐Batalla, Sonja Loges   +4 more
wiley   +1 more source

Necrosis of Pedunculated Lipofibroma by Nab-Paclitaxel

Necrosis of Pedunculated Lipofibroma by Nab-Paclitaxel
We present a rare phenomenon of a soft tumor hanging on the woman's left upper arm that underwent necrosis from the distal aspect during chemotherapy for pancreatic cancer. The benign tumor, pedunculated lipofibroma, originally had normal color for 10 years and then became necrotic when she was treated with gemcitabine and nab-paclitaxel.
openaire  

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1322-1343, March 2026.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source