Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma
BMC Cancer, 2020 Background The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing.
Zhichao Tian +7 more
doaj +1 more source
Verbessert nab-Paclitaxel die Melanom-Chemotherapie? [PDF]
Im Focus Onkologie, 2016 Trotz den Fortschritten in der Immuntherapie spielt die Chemotherapie beim metastasierten Melanom nach wie vor eine wichtige Rolle. Dies zeigt sich in einer aktuellen Phase-III-Studie, in der an Albumin-Nanopartikel gebundenes Paclitaxel (nab-Paclitaxel) mit Dacarbazin verglichen wurde.
Barbara Kreutzkamp, Carola Berking
openaire +1 more source
Thoracic Cancer, 2020 Background Previous trials have suggested that elderly patients with non‐small‐cell lung cancer (NSCLC) could benefit from nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel). Real‐world data on the elderly Chinese population are lacking.
Shuhang Wang +12 more
doaj +1 more source
Pankreaskarzinom: Langzeitdaten zu nab-Paclitaxel [PDF]
Im Focus Onkologie, 2015 Nab-Paclitaxel konnte in einer grosen Phase-III-Studie das Gesamtuberleben von Patienten mit metastasiertem Pankreaskarzinom verlangern. Nun liegen Langzeitdaten dieser Studie vor.
openaire +1 more source
A randomized phase II study of weekly nab-paclitaxel plus gemcitabine or simplified LV5FU2 as first-line therapy in patients with metastatic pancreatic cancer: the AFUGEM GERCOR trial [PDF]
, 2015 International audienceBackground : Metastatic pancreatic adenocarcinoma (PAC) prognosis remains dismal and gemcitabine monotherapy has been the standard treatment over the last decade.
Benoist Chibaudel +7 more
core +4 more sources
Therapeutic Advances in Medical Oncology, 2020 Background: The effectiveness of atezolizumab plus nab-paclitaxel for advanced triple-negative breast cancer (TNBC) has been demonstrated. We aimed to evaluate its cost-effectiveness on advanced TNBC from the US payer perspective. Methods: A Markov model
Bin Wu, Fei Ma
doaj +1 more source
Frontiers in Public Health, 2021 Purpose: The IMpassion130 trial demonstrated the efficacy of adding atezolizumab to paclitaxel for advanced or metastatic triple-negative breast cancer (TNBC).
Xiaoyan Liu +4 more
doaj +1 more source
A Randomized, Double-Blinded, Phase II Trial of Gemcitabine and Nab-Paclitaxel Plus Apatorsen or Placebo in Patients with Metastatic Pancreatic Cancer: The RAINIER Trial. [PDF]
, 2017 Lessons learnedThe addition of the heat shock protein 27 (Hsp27)-targeting antisense oligonucleotide, apatorsen, to a standard first-line chemotherapy regimen did not result in improved survival in unselected patients with metastatic pancreatic cancer ...
Al-Hazzouri, Ahmed +14 more
core +1 more source
Nab-Paclitaxel plus gemcitabine in patients with metastatic pancreatic adenocarcinoma: experience of use [PDF]
Farmacia Hospitalaria, 2015 Objective: To evaluate the results obtained with the combined use of nab-paclitaxel and gemcitabine in the treatment of patients with metastatic pancreatic adenocarcinoma. Materials and methods: Retrospective observational study.
Elena Ferris Villanueva +5 more
doaj +1 more source
Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer [PDF]
, 2019 Matrix metalloproteinase 9 (MMP9) is involved in the proteolysis of extracellular proteins and plays a critical role in pancreatic ductal adenocarcinoma (PDAC) progression, invasion and metastasis.
Awasthi, Niranjan +6 more
core +1 more source