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Plant NAD Kinase: Regulation by Calcium and Calmodulin [PDF]
, 1986 It has been shown that illumination of plant seedlings or plant tissues causes an increase of NADP and a decrease of NAD (Muto et al., 1981). So far, NAD kinase (AMP:NAD 2′- phosphotransferase; EC 2.7.1.23) has been the only enzyme which is known to catalyzes the phosphorylation of NAD to NADP.
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Trends in kinase drug discovery: targets, indications and inhibitor design
Nature Reviews Drug Discovery, 2021Helgi B Schiöth +2 more
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Kinase drug discovery 20 years after imatinib: progress and future directions
Nature Reviews Drug Discovery, 2021Darren Cross +2 more
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The role of nicotinamide riboside kinases in mammalian NAD⁺ metabolism
2017NAD+ has emerged as a central metabolic node and an important co-substrate for the activity of various enzymes, including the protein deacetylase SIRT1. Different strategies to increase NAD+ bioavailability have been shown to boost SIRT1 activity, which results in protection against metabolic disease, neurodegenerative disorders and certain types of ...
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Kinase inhibition in autoimmunity and inflammation
Nature Reviews Drug Discovery, 2021Ali A Zarrin +2 more
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Lung cancer: New biological insights and recent therapeutic advances
Ca-A Cancer Journal for Clinicians, 2011Suresh S Ramalingam +2 more
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Barata, Brian I Rini
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Kinase inhibitors: the road ahead
Nature Reviews Drug Discovery, 2018Fleur M Ferguson, Nathanael S Gray
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