Results 111 to 120 of about 11,240 (258)

Eukaryote‐Wide Distribution of a Family of Longin Domain‐Containing GAP Complexes for Small GTPases

Traffic, Volume 26, Issue 7-9, July/September 2025.
The three longin domain‐containing GAP complexes ‐ CSW, folliculin, and GATOR1 ‐ have a sporadic but pan‐eukaryotic distribution and were likely already present in LECA in some form. Their catalytic longin domains contain highly conserved sequence motifs, some of which are shared with structurally similar proteins of Asgardarchaeota.
Anna M. G. Novák Vanclová, Catherine L. Jackson, Joel B. Dacks   +2 more
wiley   +1 more source

Survey of Naegleria fowleri in geothermal recreational waters of Guadeloupe (French West Indies). [PDF]

PLoS ONE, 2013
In 2008 a fatal case of primary amoebic meningoencephalitis, due to the amoeboflagellate Naegleria fowleri, occurred in Guadeloupe, French West Indies, after a child swam in a bath fed with geothermal water.
Mirna Moussa, Johan F De Jonckheere, Jérôme Guerlotté, Vincent Richard, Alexandra Bastaraud, Marc Romana, Antoine Talarmin   +6 more
doaj   +1 more source

The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid. [PDF]

, 2013
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core ...
A Moya, A Schlessinger, AEA Hobbs, AK Dunker, AK Dunker, AM Waterhouse, B He, BA Kaufman, C Galea, CJ Brown, D Tillett, David C. Hayward, DF Bogenhagen, DF Bogenhagen, E Garner, GD Clark-Walker, George Desmond Clark-Walker, GW Daughdrill, H Dyson, H Hegyi, HJ Dyson, I Miyakawa, JD Nardozzi, JJ Ward, K Itoh, K Okamoto, K Peng, L Dente, M Ito, M Kucej, M Mbantenkhu, MA Larkin, MG Claros, MW Gray, P Tompa, PE Wright, RD Gietz, RW Gilkerson, S Meeusen, S Meeusen, Vladimir N. Uversky, X Chen, X Zuo, X Zuo, XJ Chen, Y Elbaz, Z Dosztányi, Z Dosztányi, Zsuzsanna Dosztányi   +48 more
core   +3 more sources

Fluvastatin and atorvastatin induce programmed cell death in the brain eating amoeba Naegleria fowleri.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Naegleria fowleri is the causative agent of a type of encephalitis called Primary Amoebic Encephalitis (PAM). Almost 98 % of PAM cases reported worldwide are fatal and affect mostly immunocompetent children and young adults.
Aitor Rizo-Liendo, I. Sifaoui, Iñigo Arberas-Jiménez, M. Reyes-Batlle, J. Piñero, J. Lorenzo-Morales   +5 more
semanticscholar   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Primary Amoebic Meningoencephalitis in an Infant due to Naegleria fowleri

Case Reports in Neurological Medicine, 2011
Primary amoebic meningoencephalitis (PAM) caused by free-living amebae Naegleria fowleri is a rare and fatal condition. A fatal case of primary amoebic meningoencephalitis was diagnosed in a 5-month-old infant who presented with the history of decrease ...
Vinay Khanna, Ruchee Khanna, Shrikiran Hebbar, V. Shashidhar, Sunil Mundkar, Frenil Munim, Karthick Annamalai, Deepak Nayak, Chiranjay Mukhopadhayay   +8 more
doaj   +1 more source

Lethal encounters: The evolving spectrum of amoebic meningoencephalitis

IDCases, 2019
The free-living amoebae are thermophilic organisms that may play an increasing role among diseases of a warming world. They are uncommon, accidental, yet high consequence pathogens, with differing pathologic syndromes.
Sandra G. Gompf, Cristina Garcia
doaj   +1 more source

Battling brain-eating amoeba: Enigmas surrounding immunity to Naegleria fowleri

PLoS Pathogens, 2020
Free-living amoebas (FLA) are remarkable single-cell engines, foraging their way through a range of environments. However, occasionally these amoebas find themselves within a human host, and an unusual and deadly opportunistic infection unfolds.
E. A. Moseman
semanticscholar   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

Cell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou, Yifeng Chen, Yuhao Ba, Hui Xu, Anning Zuo, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Yuqing Ren, Peng Luo, Quan Cheng, Lulu Zuo, Shanshan Zhu, Xing Zhou, Chuhan Zhang, Yukang Chen, Xinwei Han, Teng Pan, Zaoqu Liu   +18 more
wiley   +1 more source

To the knowledge of the genus Pseudospora Cienkowski [Translation from: Archiv fur Protistenkunde 59, 350-368, 1927] [PDF]

, 1981
Morphological observations on the two types of Pseudospora are given. The two Pseudospora whic are described are Pseudospora eudorini and Pseudospora volvocis.
Roskin, G.
core