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Detection of Naegleria spp. and Naegleria fowleri: a comparison of flagellation tests, ELISA and PCR
Water Science and Technology, 2003 To detect Naegleria spp, in particular Naegleria fowleri, the causative agent of human primary amoebic meningoencephalitis, a flagellation test (FT) is routinely used followed by a specific ELISA. A positive FT indicates the presence of Naegleria spp although some false negatives are likely to occur since parameters for enflagellation vary greatly.
J, Behets +6 more
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Naegleria fowleri meningoencephalitis
Blood, 2012![Figure][1] A 7-year-old boy with no prior illness or altered immunity presented to the emergency department with a 36-hour history of fever (103.7°F), emesis, headache, and lethargy. The patient had a history of swimming in a local lake the week before presentation.
Neslihan, Cetin, Douglas, Blackall
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Activation of complement by Naegleria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980Neither Naegleria nor its culture supernatant was found to be directly chemotactic for human neutrophils. Interaction of Naegleria with human serum, however, resulted in the generation of a strong chemotactic stimulus. The reduction of serum activity by heat-inactivation indicated a dependence on serum complement for the interaction.
B, Rowan-Kelly, A, Ferrante, Y H, Thong
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Cytopathogenicity of Naegleria fowleri and Naegleria gruberi for Established Mammalian Cell Cultures
The Journal of Parasitology, 1982Amebae of Naegleria fowleri and Naegleria gruberi were cytopathic for nine established mammalian cell cultures, including mouse and human fibroblasts, rabbit and monkey kidney cells, rat and mouse neuroblastoma cells, baby hamster kidney cells, and human epithelioma and carcinoma cells. Nine strains of N.
F M, Marciano-Cabral +3 more
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Naegleria and Acanthamoeba Infections: Review
Clinical Infectious Diseases, 1990Infections caused by small, free-living amebas are still unfamiliar to many clinicians, pathologists, and laboratorians. As of 31 July 1989, more than 140 cases of primary amebic meningoencephalitis caused by Naegleria fowleri and more than 40 cases of granulomatous amebic encephalitis caused by Acanthamoeba species (including two cases in patients ...
P, Ma +5 more
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Youngest Survivor of Naegleria Meningitis
The Indian Journal of Pediatrics, 2012Primary amebic meningoencephalitis (PAME) is a rare condition, usually caused by free living motile amebae. These are universally fatal infections with very few survivors reported till now. The authors report a 25-d-old boy, the youngest survivor of Naegleria meningitis. The child was admitted with a diagnosis of partially treated meningitis.
Dinesh, Yadav +4 more
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Primary Amoebic (Naegleria) Meningoencephalitis
Journal of Computer Assisted Tomography, 1982The computed tomographic (CT) appearance of a case of primary meningoencephalitis due to the free living amoeba Naegleria fowleri is presented. The cisterns around and above the midbrain and the subarachnoid spaces were obliterated on precontrast CT. Marked enhancement in these regions was seen after intravenous contrast medium administration.
A H, Lam +3 more
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Concanavalin A-Induced Agglutination of Naegleria
The American Journal of Tropical Medicine and Hygiene, 1977Concanavalin A (Con A) agglutinated all Naegleria gruberi strains tested but did not agglutinate any N. fowleri strains tested. Agglutination was time and temperature dependent and Con A concentration and ameba concentration dependent over certain ranges. Agglutination increased to maximum up to 1 h incubation with Con A.
S L, Josephson, R R, Weik, D T, John
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