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The therapeutic strategies against Naegleria fowleri
Experimental Parasitology, 2018Naegleria fowleri is a pathogenic amoeboflagellate most prominently known for its role as the etiological agent of the Primary Amoebic Meningoencephalitis (PAM), a disease that afflicts the central nervous system and is fatal in more than 95% of the reported cases.
Otavio Henrique Thiemann +4 more
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Cell and Mitochondria Respiration of Naegleria fowleri
The Journal of Parasitology, 1979Whole cell respiration rates were measured polarographically during agitated cultivation of Naegleriafowleri. During log growth, amebae consumed 30 ng atoms O/min/mg cell protein. The ameba's respiration rate gradually decreased 3-fold during stationary phase. Intact mitochondria were isolated from N.
John Dt, Weik Rr
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Naegleria fowleri: Pathogenesis, Diagnosis, and Treatment Options [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT Naegleria fowleri has generated tremendous media attention over the last 5 years due to several high-profile cases. Several of these cases were followed very closely by the general public. N.
Kris Virga, Scott Asbill, Eddie Grace
exaly +4 more sources
Amebostomes of Naegleria fowleri1
The Journal of Protozoology, 1985ABSTRACTThe strain of ameba, culture incubation temperature, and phase of ameba growth affected the number of amebostomes present on amebae of Naegleria fowleri. Serial passage of N. fowleri through mice decreased the average number of amebostomes. Amebostomes were shown to be functional by their ability to engulf yeast cells.
T. B. Cole, R. A. Bruner, D. T. John
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Agitated Mass Cultivation of Naegleria fowleri
The Journal of Parasitology, 1977Large quantities (3 X 109 amebae/liter) of Naegleria fowleri were obtained in agitated cultures using a complex medium. Logarithmic growth occurred during the initial 36 hr and the mean generation time was 5.5 hr. The maximum cell yield was 3 X 108 amebae/ml. The pH of the medium increased during logarithmic and stationary growth and the pH optimum for
Weik Rr, John Dt
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Understanding Naegleria fowleri
Water e-Journal, 2017Naegleria fowleri is warm water environmental pathogen. his paper presents information on the pathogen, its infection pathway and resulting disease, as well as the Australian historical study that provided the basis of the current potable water advice within the Australian Drinking Water Guidelines (ADWG) and results of more recent disinfection studies.
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Naegleria fowleri : Trimethoprim Sensitivity
Science, 1980Trimethoprim in a concentration of 4 micrograms per milliliter of Bacto-Casitone (Difco) medium inhibits the growth of nonvirulent Naegleria fowleri isolates. The growth of virulent strains is unaffected even with 400 micrograms of the drug per milliliter of medium.
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Biological factors affecting enflagellation of Naegleria fowleri
Journal of Bacteriology, 1982Naegleria fowleri is a pathogenic amoeboflagellate that can be evoked to transform from amoebae to flagellates by subculture to nonnutrient buffer. More than half of the amoebae of strains KUL, nN68, and Lovell became enflagellated 300 min after subculture to amoeba-saline, whereas no amoebae of strains NF66, NF69, and HB4 did. N.
D T John, T W Woodworth, S G Bradley
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Microfilaments inNaegleria fowleri amoebae
Zeitschrift für Parasitenkunde, 1976Examination by electron microscopy has revealed 2 types of microfilament in the cytoplasm of 3 strains of axenically grown Naegleria fowleri amoebae. Thin, actin-like microfilaments 5-7 nm in diameter are randomly oriented in the nonmotile amoebae, and are concentrated near the plasma membrane.
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