Results 201 to 210 of about 101,864 (307)

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

open access: yesThe FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu   +2 more
wiley   +1 more source

Correction: Multi-modal dataset creation for federated learning with DICOM-structured reports. [PDF]

open access: yesInt J Comput Assist Radiol Surg
Tölle M   +23 more
europepmc   +1 more source

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

open access: yesThe FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga   +15 more
wiley   +1 more source

When Nature Talks, Markets Move: Forecasting the Equity Premium With Eco‐Climate Incidents

open access: yesFinancial Review, EarlyView.
ABSTRACT This paper examines the role of eco‐climate information, particularly biodiversity risks, in forecasting the U.S. equity premium. Using RepRisk controversy data, we construct indicators for biodiversity, greenhouse gas emissions, and local pollution. Biodiversity indicators emerge as strong predictors of the equity premium, outperforming other
Zhiyong Li, Weiping Qin
wiley   +1 more source

Impact of 85 kHz versus 125 kHz SHIFT OCTA scan speeds on image quality in retinal diseases and diagnostic reliability of choroidal neovascular membranes. [PDF]

open access: yesSci Rep
Tran MD   +10 more
europepmc   +1 more source

Disentangling the Drivers of a Piscivorous Intra‐Annual Cohort and the Contributions of Three Cohorts to Early‐Year Class Strength in Pikeperch (Sander lucioperca)

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Using pikeperch (Sander lucioperca) as a model species, we investigated the factors influencing fluctuations in the abundance of piscivorous intra‐annual cohorts and assessed the role of three distinct cohorts: extremely small (ES), ordinary (or mid‐sized) fingerlings, and piscivorous in shaping year‐class strength.
Million Tesfaye   +21 more
wiley   +1 more source

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