Results 201 to 210 of about 362,006 (293)

Comparison of whole genome sequencing approaches for Capripox viruses. [PDF]

BMC Genomics
Breman FC, Hoffman S, Haegeman A, Philips W, de Keersmaecker S, Mileto P, Neave MJ, Bowden TR, Settypalli TBK, Lamien CE, Batten C, Wright C, De Regge N.   +12 more
europepmc   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Sleep Disturbance Trajectories During Childhood and Early Adolescence Associated With Increased Suicide Risk. [PDF]

JAACAP Open
Huber RS, Gaillard M, Sievertsen SA, Ma J, Shao S, Del Rubin DY, Jones SA, Hill AR, Bartholomeusz R, McGlade EC, Renshaw PF, Yurgelun-Todd D, Nagel BJ.   +12 more
europepmc   +1 more source

Theatres of Indirectness: Passive Aggression and Failure

Critical Quarterly, EarlyView.
Sara Crangle, Sam Ladkin
wiley   +1 more source

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source

Peripartum Cardiomyopathy Associated With Gestational Transient Thyrotoxicosis and Severe Preeclampsia: A Case Report. [PDF]

Cureus
Denis M, Mincke VL, Huart E, Nagel J, Poppe KG.   +4 more
europepmc   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

The FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva, Lena Sophie Fritsch, Leander Mika Koch, Anton Effing, Meriyem Aktas, Franz Narberhaus   +5 more
wiley   +1 more source

The role of contaminated eggshells used in poultry feed in a diffuse nationwide outbreak of <i>Salmonella</i> Enteritidis, the Netherlands, 2023 to 2025. [PDF]

Euro Surveill
Adriaansens DL, van den Berg OE, Lanzl MI, van der Weijden C, van Dommelen M, Nagel K, Batstra-Blokpoel J, Brandwagt DA, van der Zwaluw K, Mooijman K, van Hoek AH, Mans-Poulie J, van den Beld M, Castelijn G, Koene M, Slegers-Fitz-James IA, Franz E, Pijnacker R.   +17 more
europepmc   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

Artificial Intelligence Model’s assessment of intra-sample heterogeneity of HER2 IHC in breast cancer is related to interobserver and intraobserver agreement among pathologists

Ferrari PSSM, de Macedo MP, Cunha IWd, Giongo AA, Camacho AHdS, Souza AG, Rodrigues ALdB, Karlinski ÂG, Mercante AMdC, Monnerat ALC, Verdolin AA, Castro AAOL, Nicolli AC, Volpato AHC, Garibaldi BNdA, Santos CdC, Klock C, Saggioro FP, Tiburzio G, Monteiro GBM, Maximiano GNT, Vignal GM, Silva ICd, Nagel J, de Rezende LMMC, Neder L, Matushita MAM, Gaglionone NC, Barreto PSD, Peixoto RBP, Soares FA.   +30 more
europepmc   +1 more source