Results 161 to 170 of about 150,868 (264)

The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae

open access: yesActa Zoologica, EarlyView.
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi   +6 more
wiley   +1 more source

From Rating System to Thought Leadership: The Evolution of the Canada Green Building Council

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Green Building Social Movement Organizations encourage the adoption of green buildings, primarily by promoting sustainability rating tools. While numerous papers have explored the market impact of these sustainability rating tools, very few have examined either the lengthy and protracted process of their selection and enrollment by ...
J. J. McArthur   +2 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

open access: yesBrain Pathology, EarlyView.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin   +14 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Self-Induced Nail Disorders: Clinical and Demographical Features. [PDF]

open access: yesInt J Dermatol
Güldiken Doğruel G   +17 more
europepmc   +1 more source

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