Results 91 to 100 of about 180,929 (353)

Nail as a window of systemic diseases

Indian Dermatology Online Journal, 2015
Certain nail changes are specific for various dermatological disorders. In addition, examination of nails may also provide an insight into more sinister systemic manifestations in the form of both subtle as well as specific changes. These findings may present as a defect of various anatomical components of the nail unit; nail matrix, nail plate and/or ...
Archana Singal, Rahul Arora
openaire   +4 more sources

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

New insight into the pathogenesis of nail psoriasis and overview of treatment strategies

Drug Design, Development and Therapy, 2017
Alessandra Ventura,1 Mauro Mazzeo,1 Roberta Gaziano,2 Marco Galluzzo,1 Luca Bianchi,1 Elena Campione1 1Department of Dermatology, University of Rome “Tor Vergata”, Rome, Italy; 2Department of Experimental Medicine and Surgery, Rome, Italy ...
Ventura A, Mazzeo M, Gaziano R, Galluzzo M, Bianchi L, Campione E   +5 more
doaj  

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Reconstruction of Nonunion Tibial Fractures in War-Wounded Iraqi Civilians, 2006-2008: Better Late Than Never [PDF]

, 2012
OBJECTIV
Al Ani, A M K, Alras, M S, Baron, E, Daumas, L, Fakri, R M, Hérard, P, Khaddaj, S, Rose, A M C   +7 more
core   +2 more sources

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Nail Involvement as a Predictor of Disease Severity in Paediatric Psoriasis: Follow-up Data from the Dutch ChildCAPTURE Registry

Acta Dermato-Venereologica, 2018
Little is known about the relationship between nail psoriasis and psoriasis severity in children, and there has been no longitudinal assessment of psoriasis severity related to nail psoriasis.
Inge M.G.J. Bronckers, Finola M. Bruins, Maartje J. van Geel, Hans M.M. Groenewoud, Wietske Kievit, Peter C.M. van de Kerkhof, Marcel C. Pasch, Elke M.G.J. de Jong, Marieke M.B. Seyger   +8 more
doaj   +1 more source

Diseases of the Nail Unit

DeckerMed Family Medicine, 2012
The human nail is a complex unit that includes five major modified cutaneous structures: the nail matrix, nail bed, nail plate, nail folds, and cuticle (eponychium). This chapter discusses the function and structure of the five nail components and the pathophysiology affecting each.
George Cotserelis, Jennifer Nguyen
openaire   +1 more source

Sleep Disturbances and Fatigue in Adolescents with Cancer Receiving Chemotherapy [PDF]

, 2014
Sleep disturbances and fatigue are frequently complained by adolescents with cancer. These problems will lead to a variety of changes that may affect adolescents’ development.
Allenidekania, A. (Allenidekania), Rahmawaty, F. (Fetty), Waluyanti, F. T. (Fajar)   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source