Results 91 to 100 of about 158,351 (349)

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Nail Abnormalities in Thai Psoriasis Patients with Disease Severity and Impact on Quality of Life

open access: yesSiriraj Medical Journal, 2014
Background: Nail abnormalities are common in psoriasis. The relationship between nail abnormalities and disease severity or impact on quality of life has scarcely been reported. Objectives: The aims of this study were to find the proportion and types of
Sukhum Jiamton   +7 more
doaj  

Nail as a window of systemic diseases

open access: yesIndian Dermatology Online Journal, 2015
Certain nail changes are specific for various dermatological disorders. In addition, examination of nails may also provide an insight into more sinister systemic manifestations in the form of both subtle as well as specific changes. These findings may present as a defect of various anatomical components of the nail unit; nail matrix, nail plate and/or ...
Archana Singal, Rahul Arora
openaire   +4 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Choice of three different intramedullary nails in the treatment of trochanteric fractures: outcome, analysis and consideration in midterm [PDF]

open access: yes, 2019
paragone di 3 differenti impianti per frattura pertrocanterica femoreThe purpose of this study is to compare the results obtained using three different systems of osteosynthesis, developed for the surgical treatment of fractures of the trochanteric ...
De Cristo, Claudia   +7 more
core   +1 more source

New insight into the pathogenesis of nail psoriasis and overview of treatment strategies

open access: yesDrug Design, Development and Therapy, 2017
Alessandra Ventura,1 Mauro Mazzeo,1 Roberta Gaziano,2 Marco Galluzzo,1 Luca Bianchi,1 Elena Campione1 1Department of Dermatology, University of Rome “Tor Vergata”, Rome, Italy; 2Department of Experimental Medicine and Surgery, Rome, Italy ...
Ventura A   +5 more
doaj  

Liver‐specific lncRNAs associated with liver cancers

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina   +3 more
wiley   +1 more source

Meeting the challenge for foot health in rheumatic diseases [PDF]

open access: yes, 2004
Background: National guidelines recommend that patients with rheumatic diseases should have access to podiatry services and evidence is emerging that podiatry interventions are effective in the management of foot problems in this patient group.
Bowden, AP, Williams, AE
core   +1 more source

Nail disorder among patients on maintenance hemodialysis

open access: yesDermatologica Sinica, 2013
Background/Objective: Chronic renal failure can lead to nail disorders. The aim of this study was to investigate nail disorders and laboratory data in patients on constant hemodialysis (HD) in a hospital in Qazvin, Iran.
Malihe Charkhchian   +3 more
doaj   +1 more source

Diseases of the Nail Unit

open access: yesDeckerMed Family Medicine, 2012
The human nail is a complex unit that includes five major modified cutaneous structures: the nail matrix, nail bed, nail plate, nail folds, and cuticle (eponychium). This chapter discusses the function and structure of the five nail components and the pathophysiology affecting each.
George Cotserelis, Jennifer Nguyen
openaire   +1 more source

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