Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Finger nail pitting in psoriasis and its relation with different variables
Incidence of pitting, vary considerably in different types of psoriasis. In clinical practice, toe nail examination is inconvenient. There are inadequate studies which show relation of nail pitting with duration and severity of the disease. The objective
Satyendra Kumar Singh
doaj +1 more source
Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
A retrospective study on 195 horses with contaminated and infected synovial cavities [PDF]
This study analyzes the clinical aspects of contaminated and infected synovial cavities in horses and evaluates their prognosis after treatment. The medical records of 195 affected horses referred between June 1999 and July 2004 were reviewed. Twenty-six
Dewulf, Jeroen+5 more
core +1 more source
Nail lesions in red squamous lichen planus: a review of the literature
Background. Lichen planus is a chronic inflammatory disease affecting the mucous membranes, skin and its appendages. Nail lesions in lichen planus are quite common, which leads to a negative psychological and physical impact on patients.
R. V. Saranyk, T. A. Gosteva
doaj +1 more source
Polyurethanes as New Excipients in Nail Therapeutics
Onychomycosis affects about 15% of the population. This disease causes physical and psychosocial discomfort to infected patients. Topical treatment (creams, solutions, gels, colloidal carriers, and nail lacquers) is usually the most commonly required due
Barbara S. Gregorí Valdes+7 more
doaj +1 more source
Radiological Imaging of Nail Disorders (PART II) - Radiological Features of Nail Disease. [PDF]
Grover C, Bansal S, Varma A, Jakhar D.
europepmc +1 more source
Nail disease in pemphigus vulgaris
Patients affected by pemphigus vulgaris will occasionally present with associated and characteristic nail changes. This manuscript was prepared as a review of this unique presentation of pemphigus. Articles describing pemphigus vulgaris of the nail were compiled and reviewed and pertinent information was extracted to provide a concise analysis.
Serratos, Brittany Dusek+1 more
openaire +5 more sources
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion+15 more
wiley +1 more source
Investigating the efficacy and safety of calcipotriol/betamethasone dipropionate foam and laser microporation for psoriatic nail disease-A hybrid trial using a smartphone application, optical coherence tomography, and patient-reported outcome measures. [PDF]
Ortner VK+8 more
europepmc +1 more source