Results 261 to 270 of about 158,351 (349)

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort. [PDF]

Front Immunol
Yan X, Shi M, Wang B, Zeng L, Wang H, Shi J, Cui Y, Hou S.   +7 more
europepmc   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

Dermatologic toxicity occurring during anti-EGFR monoclonal inhibitor therapy in patients with metastatic colorectal cancer: A systematic review [PDF]

, 2018
Anadkat, Milan, Bohac, Chet, Garawin, Tamer, Jatoi, Aminah, Lacouture, Mario E, Mitchell, Edith   +5 more
core   +1 more source

Therapeutic effect of intramedullary reaming and nailing for long bones lengthening in children with Ollier disease and Maffucci syndrome on enchondromas: multicentric retrospective case series

Soline Bonneau, Samuel Georges, B. Fraisse, Edouard Haumont, Yan Lefèvre, Nicolas Bremond, Zagorka Péjin, Philippe Violas   +7 more
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Multiple Nail Dystrophy Associated with Human Papillomavirus Type 29 (HPV-29). [PDF]

Acta Derm Venereol
Hirano T, Egawa G, Nomura T, Kabashima K.   +3 more
europepmc   +1 more source

Nail clubbing, a dermatologic window into underlying systemic disease – an All of Us Study

Noelle Desir, Shari R. Lipner
openalex   +1 more source