Results 51 to 60 of about 71,479 (314)
256 Charcot-Marie-Tooth Disease as A Risk Factor for Periprosthetic Fractures in Tibiotalocalcaneal Fusion With Intramedullary Nailing [PDF]
, 2021 Ashwin Bhadresha +2 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Differential diagnosis of nail apparatus lesions in subungual exostosis
Лечащий ВрачBackground. Subungual exostosis is an overgrowth of bone and/or cartilage tissue in the area of the distal phalanx of the finger. The etiopathogenesis of the disease remains incompletely understood.
R. V. Saranyuk +2 more
doaj +1 more source
Advances in Rheumatology, 2019 Background Nail involvement has been described as a key clinical feature for both psoriasis (PsO) and psoriatic arthritis (PsA) and is an important risk factor in PsA.
José Alexandre Mendonça +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Dermatology Research and Practice, 2012 Melanonychia, or melanin-derived brown-to-black nail pigmentation, is a diagnostic challenge for clinicians. The most serious disease of the nail unit, melanoma, primarily presents with melanonychia. However, melanonychia most often occurs as a result of
Julie Jefferson, Phoebe Rich
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
An Analysis Of Nail Involvement In Pemphigus
Indian Journal of Dermatology, 2002 Nail involvement in pemphigus is relatively rare. A five year analysis of pemphigus cases admitted in our institute revealed 6 cases (15.6%) with nail involvement. Nail changes were part of the initial presentation along with skin and oral lesions
Vijaikumar M +3 more
doaj
The Scientific World Journal, 2014 Nail involvement has started playing a major role in the overall assessment and management of psoriatic disease. Biologics indicated for moderate to severe chronic plaque psoriasis are shown to be beneficial in nail disease.
Aikaterini Kyriakou +3 more
doaj +1 more source