Results 71 to 80 of about 158,351 (349)
Diagnostic utility of onychoscopy: Review of literature
Indian Journal of Dermatopathology and Diagnostic Dermatology, 2017 Onychoscopy is being increasingly used as a diagnostic modality for various nail diseases. Initial research had focused mainly on nail pigmentation and nailfold capillaroscopy; however, it is now being evaluated in various infectious and inflammatory ...
Chander Grover, Deepak Jakhar
doaj +1 more source
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
Dermatology Research and Practice, 2023 Background. Nail psoriasis is a challenging chronic condition affecting patients functionally and psychologically. Nail involvement is observed in 15–80% of psoriatic patients with occasional presence of isolated nail psoriasis. Objectives.
Zeinab R. Mashal +3 more
doaj +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
In vitro efficacy of tavaborole topical solution, 5% after penetration through nail polish on ex vivo human fingernails [PDF]
, 2018 This document is the Accepted Manuscript of the following article: Aditya K. Gupta, et al, 'In vitro efficacy of tavaborole topical solution, 5% after penetration through nail polish on ex vivo human fingernails', Journal of Dermatological Treatment, Jan
Aditya K. Gupta +10 more
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Complex interaction of sensory and motor signs and symptoms in chronic CRPS. [PDF]
, 2011 Spontaneous pain, hyperalgesia as well as sensory abnormalities, autonomic, trophic, and motor disturbances are key features of Complex Regional Pain Syndrome (CRPS).
Azad, Shahnaz Christina +7 more
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An Analysis Of Nail Involvement In Pemphigus
Indian Journal of Dermatology, 2002 Nail involvement in pemphigus is relatively rare. A five year analysis of pemphigus cases admitted in our institute revealed 6 cases (15.6%) with nail involvement. Nail changes were part of the initial presentation along with skin and oral lesions
Vijaikumar M +3 more
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source