Results 121 to 130 of about 236,152 (278)
Summary Background The Psoriasis Area and Severity Index (PASI) is the standard measure for psoriasis severity but reflects only a single time point and may underestimate long‐term disease burden. To assess whether the highest‐ever recorded PASI (PeakPASI) can serve as a marker of historical disease severity and correlate with treatment burden and ...
Simran Wilkhoo +6 more
wiley +1 more source
AI‐Assisted Fungal Detection in Dermatopathology: A Study on Accuracy, Efficiency, and Usability
Summary Background and Objectives AI‐based image analysis is increasingly applied in pathology. Excluding fungal elements in PAS‐stained skin sections is labor‐intensive and well suited for AI assistance. While fungal detection in nails has been studied, skin‐biopsy applications and real‐world benefit remain limited.
Paul Schmidle +12 more
wiley +1 more source
SUMMARY Digital transformation is fundamentally reshaping dermatology, creating new opportunities in diagnostics, therapy, and healthcare organization. Large datasets combined with Artificial Intelligence (AI) enable more precise classification and prognosis, particularly through the analysis of clinical and dermoscopic imaging.
Lea Henkel +17 more
wiley +1 more source
Nail involvement in psoriasis is common. It is seen in up to 80% of patients with psoriatic lesions and may be the only manifestation in 6% of cases. Nail psoriasis is correlated with more severe disease, characterized by earlier onset and a higher risk of psoriatic arthritis.
Canal-García E +3 more
openaire +2 more sources
Summary Background and Objectives Closed venereology wards existed in both Western and Eastern European dictatorships. These institutions isolated, disciplined, and “educated” individuals with Sexually Transmitted Infections (STI) or suspected infections.
Maximilian Schochow, Florian Steger
wiley +1 more source
Dermoscopic nail findings in childhood psoriasis
Background and Design: Nail dermoscopy or onychoscopy refers to the examination of the nail unit which consists of the proximal and lateral nail folds, hyponychium, nail plate and nail bed non-invasively.
Zindanci, Ilkin +2 more
core +1 more source
Treatment of Nail Psoriasis: Common Concepts and New Trends
The lifetime incidence of nail involvement in psoriatic patients is estimated to be 80–90%, and the nails can be affected in 10% to 55% of psoriatic patients.
Yasemin Oram, A. Deniz Akkaya
doaj +1 more source
Biogenesis of TNF‐α‐insights into proteostasis and inflammation
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar +3 more
wiley +1 more source
Background and Objective. Psoriasis is a common chronic inflammatory skin disorder affecting any age and gender. The clinical presentation of the nail disease depends on the location of the pathology: nail bed or nail matrix.
Nasrin Saki +4 more
doaj +1 more source
Nail Psoriasis: A Review of Treatment
Nail psoriasis is a common and disabling manifestation of cutaneous plaque-type psoriasis. Treatment of nail psoriasis is often unsuccessful and frequently requires prolonged and tedious treatment regimens to achieve or maintain remission. The clinician
Todd A. Kerensky, Alice B. Gottlieb
core +1 more source

