Results 11 to 20 of about 159,625 (206)

Dynamics of vortex shedding from slender cones [PDF]

open access: yes, 2009
PhDThe dynamics of vortex shedding from bluff bodies has been investigated experimentally for many decades, with the simple geometric case for the investigation being a uniform circular cylinder aligned with its axis normal to the flow. Even though
Jagadeesh, Chetan Sakaleshpur
core   +4 more sources

Systematic investigation of different formulations for drug delivery through the human nail plate "in vitro" [PDF]

open access: yes, 2010
Human nails do not have only protective and decorative role, but can also be considered as an alternative pathway for drug delivery, especially in nail diseases such as onychomycosis or psoriasis.
Vejnoviċ, Ivana
core   +1 more source

Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008

open access: yesEmerging Infectious Diseases, 2011
Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by onychomadesis (nail shedding), occurred during summer and fall 2008 in Valencia, Spain.
Maria A. Bracho   +4 more
doaj   +1 more source

Whole exome sequencing reveals novel somatic alterations in neuroblastoma patients with chemotherapy

open access: yesCancer Cell International, 2018
Background We ought to explore the acquired somatic alterations, shedding light on genetic basis of somatic alterations in NB patients with chemotherapy. Methods Marrow blood samples from NB patients were collected before treatment, after the 2nd and 4th
Chao Duan   +10 more
doaj   +1 more source

Modeling Sudden Ice Shedding from Conductor Bundles [PDF]

open access: yes, 2012
Sudden ice shedding from conductor bundles was modeled numerically and experimentally by improving the approaches proposed formerly for a single cable. The experimental study was carried out on a small-scale laboratory model of one span of a twin bundle.
Kollar, László E., Farzaneh, Masoud
core   +1 more source

Vibration of Bundled Conductors Following Ice Shedding [PDF]

open access: yes, 2008
The dynamic behavior of bundled conductors following ice shedding from one subconductor is examined numerically using the finite-element method. An existing model of ice shedding from a single conductor is improved by developing a model of spacers which ...
Kollar, László E., Farzaneh, Masoud
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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