Results 71 to 80 of about 159,625 (206)

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

Farm labor scarcity and its uneven impacts on crop producers in the United States

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract This study is the first to evaluate the impacts of farm labor scarcity on producers in the United States across different crop production systems. Between 2002 and 2017, we disentangle the effects of labor scarcity from the impacts of rising commodity demand, technological change, and supply of other inputs on labor market outcomes.
Srabashi Ray   +4 more
wiley   +1 more source

Firearm carrying practices and motivations: A mixed methods study among adults and youth

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract The purpose of this participatory action, mixed methods research study was to identify motivations related to firearm carrying from a qualitative perspective, and then to use quantitative research to characterize the patterns of motivations around carrying.
Krista R. Mehari   +5 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Gang-nail: manual técnico

open access: yes, 1975
paginación ...

core  

Immigration detention centers as torturing environments: Ethical reckonings, radical refusals, and implications for a psychology of resistance

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This paper examines psychologists' ethical dilemmas in immigration detention centers. Using critical psychology, border, and detention scholarship, it highlights psychologists' historical complicity in state violence, from the U.S. Enhanced Interrogation Program to current border regimes.
Francesca Esposito   +6 more
wiley   +1 more source

Owning Home, Finding Belonging: Relational Meanings of Homeownership for Migrant Healthcare Workers in Australia

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Migrant healthcare workers in Australia find themselves at the centre of three intersecting concerns, often presented as ‘crises’ in contemporary discourse: the ‘care crisis’, the ‘housing crisis’ and the ‘migration crisis.’ Yet their own perspectives on these issues are rarely foregrounded. This paper explores the role of homeownership in the
Leah Williams Veazey
wiley   +1 more source

Nail involvement in psoriatic arthritis

open access: yes, 2017
Nail psoriasis is considered a significant psychological and social problem causing functional impairment in affected patients. Nail changes hamper their daily and occupational activities and contribute to a worse quality of life.
Piotr Sobolewski   +2 more
core   +1 more source

Animal stroke models and outcome evaluation: A review

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba   +2 more
wiley   +1 more source

Nail colour changes (chromonychia)

open access: yes, 2005
There are some important points to note concerning the examination of abnormal nails for colour changes. The nails should be studied with the fingers completely relaxed and not pressed against any surface.

core   +1 more source

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