Advanced Science, EarlyView.This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He +7 more
wiley +1 more source
Novel CT-based simulation reveals anterolateral surgical approach avoids acromial collision in antegrade humeral nailing. [PDF]
Eur J Trauma Emerg SurgArnhold R +4 more
europepmc +1 more source
Evaluation of Risk Factors for Revision Surgery After Proximal Femoral Nailing for Intertrochanteric Fractures [PDF]
Evrim Duman +5 more
openalex +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases
Advanced Science, EarlyView.Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh +17 more
wiley +1 more source
Salvage Total Hip Arthroplasty After Cephalomedullary Nail Failure Due to Nonunion in a Pertrochanteric Fracture: A 10-Year Follow-Up. [PDF]
CureusZmerly H +4 more
europepmc +1 more source
Clinical measurement of femur length as a guide to choose the size of cephalic lag screw (calcar screw) in proximal femur nailing surgery [PDF]
Gaurav Kumar Singh +4 more
openalex +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida +9 more
wiley +1 more source
Quantification of Articular Surface Involvement During Intramedullary Fixation of the Phalanges. [PDF]
J Hand Surg Glob OnlineMekhail J +5 more
europepmc +1 more source