Results 21 to 30 of about 47,534 (256)

Advanced nail surgery

Journal of Cutaneous and Aesthetic Surgery, 2011
Six techniques not yet widely known or used in the dermatologic surgery of the nails are briefly described. Small-to-medium-sized tumours of the proximal nail fold (PNF) can be excised and the defect repaired with advancement or rotation flaps. A superficial biopsy technique of the matrix for the diagnosis of longitudinal brown streaks in the nail ...
openaire   +5 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Bone-conserving radiation-free intramedullary nail removal technique: A prospective surgical study on 108 patients with healed tibia fractures

Asian Journal of Medical Sciences, 2023
Background: While attempting hardware removal, intraoperative challenges and hardware removal strategy vary in each case. Only a few nail removal techniques are reported in the literature.
Nishit Palo , Chhavi Malik , Abhishek Shukla, Govind Narayan Choudhary , Veerendra Mannan , Rakesh Kumar G   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Accidental pneumatic nail gun brain injury in a teenager: A case report and review of the literature

Interdisciplinary Neurosurgery, 2023
Background: Pneumatic nail gun brain injury has been increasing in recent years. This injury may accidentally occur by pneumatic nail gun devices or after a suicide attempt. Most pediatric patients develop nail gun brain injury after an accidental event.
Shahnam Baboli, Simin Baboli, Mehdi Sakhabakhsh, Saeed Soleiman-Meigooni   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Comparing the therapeutic efficacy of endoscopic minimally invasive surgery and traditional surgery for early-stage breast cancer: A meta-analysis

Open Medicine
Early-stage breast cancer requires effective surgical interventions. This meta-analysis compares the therapeutic efficacy of endoscopic minimally invasive surgery (EMIS) with traditional surgery, such as modified radical mastectomy.
Ma Qiyi, Shi Tingting, Wang Huan, Xing Jie   +3 more
doaj   +1 more source

Aesthetic satisfaction of patients following plastic surgery of nail folds combined with conservative nail plate reconstruction for ingrown toenails

Frontiers in Medicine
IntroductionManagement of ingrown toenails encompasses a wide range of methods, from conservative to surgical approaches, which vary in terms of final aesthetic outcomes and overall patient satisfaction.AimThis study aimed to assess patient aesthetic ...
Tomasz Trochanowski, Tomasz Trochanowski, Tomasz Trochanowski, Aleksandra Dańczak Pazdrowska, Ewa Baum   +4 more
doaj   +1 more source

Small Incision Osteotomy: An Innovative Approach for Removal of Impacted Kuntscher Nail [PDF]

Journal of Clinical and Diagnostic Research, 2019
The use of Kuntscher nail has been one of the most important advancement in trauma surgery. Removal of impacted Kuntscher nail represents one of the difficult problems in orthopaedics today.
Vishal Kumar, Chirag Arora, Sameer Aggarwal   +2 more
doaj   +1 more source