Results 61 to 70 of about 3,079,778 (336)

A systematic review and meta‐analysis of randomised controlled trials of surgical treatments for ingrown toenails part II: healing time, post‐operative complications, pain, and participant satisfaction

Journal of Foot and Ankle Research, 2023
Background When performing nail surgery, clinicians must choose from a multitude of procedures and variations within each procedure. Much has been published to guide this decision making, but there are a lack of up to date robust systematic reviews to ...
Victoria Exley, Katherine Jones, Grace O'Carroll, Judith Watson, Michael Backhouse   +4 more
doaj   +1 more source

Choice of three different intramedullary nails in the treatment of trochanteric fractures: outcome, analysis and consideration in midterm [PDF]

, 2019
paragone di 3 differenti impianti per frattura pertrocanterica femoreThe purpose of this study is to compare the results obtained using three different systems of osteosynthesis, developed for the surgical treatment of fractures of the trochanteric ...
De Cristo, Claudia, Formica, Alessandro, Graci, Jole, Grasso, Raffaele, Gurzì, Michele, Persiani, Pietro, Ranaldi, Filippo Maria, Villani, Ciro   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Penetrating cardiac trauma caused by a nail-gun: A case report and narrative review

Trauma Case Reports, 2022
Introduction: Penetrating cardiac injuries are emergencies that require prompt surgical management. Most of these injuries are caused by gunshots or stab wounds however the incidence of nail-gun injuries is rising due to their availability and widespread
A. Eranki, A. Wilson-Smith, C. Villanueva, P. Seah   +3 more
doaj   +1 more source

Cadaveric simulation for improving surgical training in dermatology. [PDF]

, 2018
Simulation models are rapidly changing medical education, especially the training of dermatology residents. Various models are available, including cadaveric simulations.
Connolly, Deirdre, Griffin, Thomas, Hazan, Ezra, Keller, Matthew, Torbeck, Richard, Trufant, Joshua, Wang, Jordan V.   +6 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Exploring subungual onycholemmal cysts: A rare case report and comprehensive literature review

Clinical Case Reports
Key clinical message Subungual Onycholemmal Cyst (SOC) is a rare nail abnormality with different clinical presentations which can mimic different nail malignancies, such as melanoma, SCC, or glomus tumor.
Toktam Safari Giv, Mahdiyeh Movahedi, Sahar Dadkhahfar, Farsad Biglari, Azadeh Rakhshan, Ghazal Mardani, Meisam Jafari Kafiabadi   +6 more
doaj   +1 more source

Fatigue strength of common tibial intramedullary nail distal locking screws [PDF]

, 2009
Premature failure of either the nail and/or locking screws with unstable fracture patterns may lead to angulation, shortening, malunion, and IM nail migration.
Lanny V Griffin, Robert M Harris, Joseph J Zubak, EA Nicoll, JF Haines, A Sarmiento, RL Batten, T Ruedi, J Thunold, CM Court-Brown, G De Bastiani, G Kuntscher, GB Kuntscher, JO Lottes, K Klemm, LB Bone, LB Bone, CJ Hindley, UW Boenisch, GA Melcher, RA Winquist, JB Morrison, JF Keating, P Schandelmaier, SW Robertson, DA Runyan   +25 more
core   +3 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

A systematic review and meta‐analysis of randomised controlled trials on surgical treatments for ingrown toenails part I: recurrence and relief of symptoms

Journal of Foot and Ankle Research, 2023
Background Ingrown toenails are a common nail pathology. When conservative treatments are ineffective, a surgical approach is often utilised. Despite recent narrative reviews, there is a need for an up‐to‐date and rigorous systematic review of surgical ...
Victoria Exley, Katherine Jones, Grace O'Carroll, Judith Watson, Michael Backhouse   +4 more
doaj   +1 more source