Results 61 to 70 of about 1,134 (197)

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning   +7 more
wiley   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Engineering Strategies to Suppress Thermal Runaway Propagation in Lithium‐Ion Battery: Mechanisms, Metrics, Materials, and Evaluation Methods

open access: yesAdvanced Science, EarlyView.
Thermal runaway propagation can transform a single‐cell failure into a system‐level hazard in lithium‐ion battery packs. This review clarifies how heat transfer, gas venting, combustion, and configuration govern cell‐to‐cell failure, and links measurable metrics, pathway‐oriented suppression materials, and experimental/modeling tools to guide safer ...
Jinrong Su   +15 more
wiley   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

Overcoming Interfacial Hurdles in Solid‐State Aluminum Batteries for Safe and Energy‐Dense Storage

open access: yesAdvanced Science, EarlyView.
Solid‐state aluminum batteries (SSABs) promise high energy density and intrinsic safety but face severe solid–solid interfacial challenges. This review reveals the three core hurdles—anode passivation, cathode contact loss, and electrolyte grain boundary resistance and discusses strategies including artificial interphases, alloying, and composite ...
Yunlei Wang   +5 more
wiley   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

open access: yesAdvanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels   +2 more
wiley   +1 more source

Ductile B2 Intermetallics‐Driven Strength‐Ductility Synergy in Heterolaminated Multi‐Principal Element Alloys

open access: yesAdvanced Science, EarlyView.
Intrinsic phase toughening transforms a brittle B2 intermetallic into a plastically deformable, load‐bearing phase, while a heterogeneous laminated architecture suppresses strain localization and interface cracking. The synergy between ductile intermetallics and mesoscale heterogeneity establishes a general design strategy for breaking the long ...
Lu Yang   +9 more
wiley   +1 more source

From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra   +2 more
wiley   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

open access: yesAdvanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim   +5 more
wiley   +1 more source

Decoupling Chemical and Mechanical Contributions to Capacity Fading in Ni‐Rich Cathodes for Sulfide‐Based All‐Solid‐State Batteries

open access: yesAdvanced Energy Materials, EarlyView.
Ni‐rich cathodes in sulfide‐based ASSBs undergo intertwined (electro)chemical and mechanical degradation. Here, a new diagnostic framework is presented to decouple each contribution by partitioning capacity fading into charge and discharge fading.
Jangwhan Seok   +12 more
wiley   +1 more source

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