Results 11 to 20 of about 256,652 (307)

MiRNAs in cancer therapy: focusing on their bi-directional roles [PDF]

open access: yesExRNA, 2019
MicroRNA (miRNA) dysregulation is causal in most, if not all, cancers. They silence the gene’s expression by modulating messenger RNA (mRNA) through employing translational repression or degradation.
Wei He   +4 more
doaj   +1 more source

Nail biology and nail science [PDF]

open access: yesInternational Journal of Cosmetic Science, 2007
SynopsisThe nail plate is the permanent product of the nail matrix. Its normal appearance and growth depend on the integrity of several components: the surrounding tissues or perionychium and the bony phalanx that are contributing to the nail apparatus or nail unit.The nail is inserted proximally in an invagination practically parallel to the upper ...
de Berker, David A   +2 more
openaire   +3 more sources

Identification of Fungi Involved in Onychomycosis in Patients of a Spanish Rural Area

open access: yesJournal of Fungi, 2021
Onychomycosis is one of the most frequent reasons for visiting podiatrist clinics. Complementary tests and the accurate identification of the infectious agents are key issues for a successful treatment of onychomycosis.
Felix Marcos-Tejedor   +4 more
doaj   +1 more source

Blue man: Ochronosis in Otolaryngology

open access: yesClinical Case Reports, 2022
Blue discoloration of the skin and cartilage, or ochronosis, is a rare physical examination finding. We present two cases of childhood onset ochronosis, one exogenous and one endogenous in etiology. The first was caused by minocycline use for severe acne,
Karuna Dewan   +2 more
doaj   +1 more source

Distinctive nail pattern following androgen replacement therapy

open access: yesIJU Case Reports, 2022
Introduction A distinctive nail pattern in a patient undergoing androgen replacement therapy is presented hereby. Case presentation A 47‐year‐old male patient noticed a peculiar “washboard‐like” pattern on his fingernails. He had been undergoing androgen
Ippei Miyata, Atsushi Nagai
doaj   +1 more source

Picture-Hanging Puzzles [PDF]

open access: yes, 2012
We show how to hang a picture by wrapping rope around n nails, making a polynomial number of twists, such that the picture falls whenever any k out of the n nails get removed, and the picture remains hanging when fewer than k nails get removed.
D. Rolfsen   +17 more
core   +6 more sources

Comparative and evolutionary analyses of the divergence of plant oligosaccharyltransferase STT3 isoforms

open access: yesFEBS Open Bio, 2020
STT3 is a catalytic subunit of hetero‐oligomeric oligosaccharyltransferase (OST), which is important for asparagine‐linked glycosylation. In mammals and plants, OSTs with different STT3 isoforms exhibit distinct levels of enzymatic efficiency or ...
Guanting Niu   +5 more
doaj   +1 more source

The control of dead space with antibiotic loaded cement beads and nails in high energy trauma [PDF]

open access: yesTrakia Journal of Sciences, 2017
Purpose: To treat delayed present (more than 24h) and Gustilo type III fractures in a better way than external fixation which before was a routine in our hospital. Methods: We have applied advanced trauma life support control (ATLS).
A. Al-Sadek   +3 more
doaj   +1 more source

Platonic interpretive strategies, and the history of philosophy, with a comment on Renaud

open access: yesPlato, 2017
François Renaud replies to the question of what principles one ought to employ in the study of Plato by arguing that, and demonstrating how, the argument and the drama operate together successfully in the Gorgias.
Debra Nails
doaj   +1 more source

Gain of Metabolic Benefit with Ablation of miR-149-3p from Subcutaneous Adipose Tissue in Diet-Induced Obese Mice

open access: yesMolecular Therapy: Nucleic Acids, 2019
The global rise in obesity has become a public health crisis. During the onset of obesity, disrupted catecholamine signals have been described to contribute to excess fat accumulation, however, the molecular and metabolic change of subcutaneous adipose ...
Shasha Zheng   +15 more
doaj   +1 more source

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