Results 31 to 40 of about 2,649 (175)

Pattern of peripapillary capillary density loss in ischemic optic neuropathy compared to that in primary open-angle glaucoma. [PDF]

PLoS ONE, 2018
Both non-arteritic anterior ischemic optic neuropathy (NAION) and primary open-angle glaucoma (POAG) damage retinal ganglion cell axons, which are perfused by the radial peripapillary capillaries.
Masoud Aghsaei Fard, Yanin Suwan, Sasan Moghimi, Lawrence S Geyman, Toco Y Chui, Richard B Rosen, Robert Ritch   +6 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis

VIEW, EarlyView.
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian, Keke Zhang, Wenwen He, Yan Ke, Yi Lu, Xiangjia Zhu   +5 more
wiley   +1 more source

Prevalence of Asymptomatic NAION in the Fellow Eye of Patients With Acute NAION

, 2022
Sequential episodes of nonarteritic anterior ischemic optic neuropathy (NAION) are reportedly uncommon, occurring in approximately 15% of cases. Despite this, visual field (VF) defects are often present in \u27unaffected\u27 eyes though their etiology ...
Natalie Brossard; Laura Donaldson; Edward Margolin
core  

Comparison of Optic Nerve Head Morphology in Patients with Primary Open Angle Glaucoma and Non-Arteritic Anterior Ischemic Optic Neuropathy

Acta Clinica Croatica, 2017
The aim of this study was to assess damage to retinal ganglion cells (RGC) and morphology of the optic nerve head (ONH) in patients with primary open angle glaucoma (POAG) and non-arteritic anterior ischemic optic neuropathy (NAION).
Darija Jurišić, Katia Novak Lauš, Irena Sesar, Tomislav Kuzman   +3 more
doaj   +1 more source

Deep learning system for distinguishing optic neuritis from non-arteritic anterior ischemic optic neuropathy at acute phase based on fundus photographs

Frontiers in Medicine, 2023
PurposeTo develop a deep learning system to differentiate demyelinating optic neuritis (ON) and non-arteritic anterior ischemic optic neuropathy (NAION) with overlapping clinical profiles at the acute phase.MethodsWe developed a deep learning system ...
Kaiqun Liu, Shaopeng Liu, Xiao Tan, Wangting Li, Ling Wang, Xinnan Li, Xiaoyu Xu, Yue Fu, Xiaoning Liu, Jiaming Hong, Haotian Lin, Hui Yang   +11 more
doaj   +1 more source

Ischaemic Optic Neuropathy After Cardiac Surgery: A Systematic Review and Meta‐Analysis of Incidence and Risk Factors

ANZ Journal of Surgery, EarlyView.
Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar, Ammar Zaka, Amitouj S. Sidhu, Shahi Goswami, Aditi Singh, Jordan Ng, Brandon Stretton, Joshua G. Kovoor, Aashray K. Gupta, Stephen Bacchi, Weng Onn Chan, Celia Chen   +11 more
wiley   +1 more source

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi, Filip Gnesin, Baker Nawfal Jawad, Zia Niazi, Puriya Daniel Wuertz Yazdanfard, Anne P. Toft‐Petersen, Kathrine Kold Sørensen, Amani Meaidi, Yousif Subhi, Christian Torp‐Pedersen   +9 more
wiley   +1 more source

Association Study of MTHFR Polymorphisms with Nonarteritic Anterior Ischemic Optic Neuropathy in a Spanish Population

Biomedicine Hub, 2020
Introduction: Nonarteritic anterior ischemic optic neuropathy (NAION), painless loss of central and/or peripheral vision, is a multifactorial disease caused by insufficient blood flow through the posterior ciliary arteries to the optic nerve head ...
Beatriz Fernández-Vega, Lydia Álvarez, Montserrat García, Enol Artime, Marta Diñeiro Soto, Javier Nicieza, José A. Vega, Héctor González-Iglesias   +7 more
doaj   +1 more source

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

Journal of Internal Medicine, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source