Results 91 to 100 of about 390,931 (263)

Genotype–Phenotype Correlations of Li–Fraumeni Syndrome in Japan Children's Cancer Group LFS20 Study Cohort

Cancer Science, EarlyView.
This study investigates genotype–phenotype correlations in Japanese families with germline TP53 pathogenic variants, collected through a nationwide prospective cancer surveillance study (JCCG LFS‐20). Among 41 families analyzed, 36 met criteria for Li–Fraumeni syndrome (LFS), and 5 were classified as attenuated LFS.
Fumito Yamazaki, Yoshiko Nakano, Masashi Sanada, Hiroki Kurahashi, Shunsuke Miyai, Arisa Ueki, Yuko Watanabe, Daisuke Hasegawa, Shuhei Karakawa, Toshifumi Ozaki, Akira Hirasawa, Akiko M. Saito, Eisuke Inoue, Motohiro Kato, Hiroyoshi Hattori   +14 more
wiley   +1 more source

Nakano's theorem revisited. [PDF]

Michigan Mathematical Journal, 1976
Aliprantis, C. D., Burkinshaw, O.
openaire   +2 more sources

Nakano-Nadel type, Bogomolov-Sommese type vanishing and singular dual Nakano semi-positivity

, 2022
In this article, we get properties for singular (dual) Nakano semi-positivity and obtain singular type vanishing theorem involving $L^2$-subsheaves on weakly pseudoconvex manifolds by $L^2$-estimates and $L^2$-type Dolbeault isomorphisms. As applications, Fujita's conjecture type theorem with singular Hermitian metrics is presented.
openaire   +2 more sources

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

Journal of Experimental Medicine, 1999
Secondary lymphoid organ chemokine (SLC) is expressed in high endothelial venules and in T cell zones of spleen and lymph nodes (LNs) and strongly attracts naive T cells.
M. Gunn, S. Kyuwa, Carmen Tam, T. Kakiuchi, A. Matsuzawa, L. Williams, H. Nakano   +6 more
semanticscholar   +1 more source

Role of freshwater availability and terrestrial land‐cover change in the distribution of a declining, terrestrial, insectivorous bird

Conservation Biology, EarlyView.
Abstract Insectivorous, Afro‐Palearctic migrant birds provide cross‐border ecosystem services, but many are declining rapidly. The complex life cycle of migrant birds makes their conservation difficult, but understanding where they spend time during the breeding season can help indicate where those actions will be most effective.
Catrin F. Eden, Simon Gillings, Richard K. Broughton, Bart Donato, Chris M. Hewson, Stuart P. Sharp   +5 more
wiley   +1 more source

Board Size in Context: A Meta‐Analysis on the Relationship Between Board Size and Firm Performance

Corporate Governance: An International Review, EarlyView.
ABSTRACT Research Question/Issue Research presents mixed findings on the relationship between board size and firm performance. Acknowledging that larger boards simultaneously offer increased resources and face heightened coordination demands, we propose that the ongoing ambiguity in this relationship stems from the context‐dependent nature of how ...
Fabian K. Ahrens, Dennis B. Veltrop, Laetitia B. Mulder, Floor Rink   +3 more
wiley   +1 more source

Nakano teoremi

, 2020
In this thesis, it has been researched that in which circumstances it can be true which is known as Nakano Theorem, is generalized in . For this reason, the related parts of essay of W. A. J. Luxemburg and B. De Pagter, that is named by ?Maharam extensions of positive operators and f-modules?, has examined in a detailed way and it has tried research to
openaire   +1 more source

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

Genes & Development, 2008
Silencing of transposable elements occurs during fetal gametogenesis in males via de novo DNA methylation of their regulatory regions. The loss of MILI (miwi-like) and MIWI2 (mouse piwi 2), two mouse homologs of Drosophila Piwi, activates retrotransposon
Satomi Kuramochi-Miyagawa, Toshiaki Watanabe, Kengo Gotoh, Y. Totoki, A. Toyoda, M. Ikawa, Noriko Asada, K. Kojima, Y. Yamaguchi, T. Ijiri, K. Hata, E. Li, Y. Matsuda, Tohru Kimura, M. Okabe, Y. Sakaki, H. Sasaki, T. Nakano   +17 more
semanticscholar   +1 more source

On the Nakano vanishing theorem

, 2020
In this note, we state various generalisations of the Nakano vanishing theorem under weak positivity assumptions, and compare them with the known results.
openaire   +2 more sources

Clinical Outcomes of Reduced‐Dose Cabozantinib as Third‐ or Later‐Line Therapy After Immune Checkpoint Inhibitors in Advanced Hepatocellular Carcinoma: A Real‐World Study

Hepatology Research, EarlyView.
In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya, Hisanori Muto, Yoshihiko Tachi, Mizuki Ariga, Sayaka Morisaki, Gakushi Komura, Takuji Nakano, Hiroyuki Tanaka, Kazunori Nakaoka, Eizaburo Ohno, Kohei Funasaka, Mitsuo Nagasaka, Ryoji Miyahara, Yoshiki Hirooka   +13 more
wiley   +1 more source