Results 241 to 250 of about 9,311,206 (347)

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms. Corrigendum. [PDF]

open access: yesActa Crystallogr F Struct Biol Commun
Sharma M   +4 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Record linkage in public health datasets: a practical experience in a fast in-process analytical database. [PDF]

open access: yesRev Bras Epidemiol
Tassinari W   +7 more
europepmc   +1 more source

Association of Industry Payments to Physicians With the Prescribing of Brand-name Statins in Massachusetts.

open access: yesJAMA Internal Medicine, 2016
J. Yeh   +4 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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