Results 291 to 300 of about 9,311,206 (347)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Introducing the ADFM (Reach) Committee. [PDF]

Ann Fam Med
Nair S, Schickedanz H, Peek CJ, Elwood S, ADFM REACH Committee.   +4 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Isosakuranetin ameliorates hypertension in rats induced by L-NAME. [PDF]

J Pharm Health Care Sci
Pantan R, Chokchaisiri R, Suksamrarn A, Tocharus C.   +3 more
europepmc   +1 more source

Correction: From fishing village to atomic town and present: A grounded theory study. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Correction: Trend change in delayed first antenatal care visit among reproductive‑aged women in ethiopia: multivariate decomposition analysis. [PDF]

Reprod Health
Gebeyehu AA, Muche AA, Woldemariam M, Yenew C, Atikilt G, Andualem M, Mebrat A.   +6 more
europepmc   +1 more source

Taxonomic and nomenclatural history of <i>Neckera</i> (Bryophyta, Neckeraceae), including reinstatement of <i>Rhystophyllum</i>, the correct name for a segregate of this genus. [PDF]

PhytoKeys
Ochyra R, Plášek V, Brinda JC.
europepmc   +1 more source

Identifying racialized administrative and criminal legal burdens for obtaining gender-affirming identification documents among transgender groups: a qualitative analysis. [PDF]

Health Justice
Nowotny K, Hummel C, Ramos B, McKenzie J, Mayfaire A, Truong-Vu KP, Copeland C.   +6 more
europepmc   +1 more source

NPCDR 2.0: the activity and structure landscape of natural product-based drug combination. [PDF]

Nucleic Acids Res
Gao Q, Yu X, Liu K, Zhu Z, Chen M, Zhao X, Liao Z, Xu L, Zhou Y, Zhu F, Sui X.   +10 more
europepmc   +1 more source