Results 91 to 100 of about 27,584,206 (303)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A review of SDN‐enabled routing protocols for Named Data Networking

Engineering Reports
Named Data Networking is a novel network architecture for the future internet in which data is named rather than addressed. This enables routers to forward data more efficiently based on its name, outperforming IP‐based routing.
Sembati Yassine, Naja Najib, Jamali Abdellah   +2 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Optimising Selective Sampling for Bootstrapping Named Entity Recognition [PDF]

, 2005
Training a statistical named entity recognition system in a new domain requires costly manual annotation of large quantities of in-domain data. Active learning promises to reduce the annotation cost by selecting only highly informative data points.
Hachey, Benjamin Clayton, Hachey, Ben, Grover, Claire, Grover, Claire; id_orcid, Alex, Beatrice, Becker, Markus   +5 more
core  

CSS-LSTM: An Intelligent Caching Strategy in NDN Clusters

Acta Technica Jaurinensis
In-network caching is a key aspect of Named Data Networking (NDN) due to its significant impact on network performance and data delivery efficiency. As content demand, particularly for multimedia, continues to grow, deciding what to cache, where to store
Ibrahim Khalil Douis, Hafida Bouziane, Abdallah Chouarfia   +2 more
doaj   +1 more source

Using a Distributed Roadside Unit for the Data Dissemination Protocol in VANET With the Named Data Architecture

IEEE Access, 2018
Vehicular ad hoc network (VANET) has recently become one of the highly active research areas for wireless networking. Since VANET is a multi-hop wireless network with very high mobility and intermittent connection lifetime, it is important to effectively
Sasirom Tiennoy, Chaiyachet Saivichit
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Data Curation Network Strategic Framework 2022-2025 v1.0

, 2022
As we grow and evolve, it’s vital that we stay true to our mission as an organization. In 2021, we began a process to outline a strategic framework for continued growth while further cementing our role within the broader data sharing community.
Data Curation Network
core