Results 41 to 50 of about 24,525,634 (237)
Mediator-assisted multi-source routing in information-centric networks [PDF]
, 2016 Among the new communication paradigms recently proposed, information-centric networking (ICN) is able to natively support content awareness at the network layer shifting the focus from hosts (as in traditional IP networks) to information objects. In this
Laura Carrea +7 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Name Lookup in Named Data Networking: A Review
Information, 2019 Named data networking (NDN) is an alternative model to the current traditional IP-based Internet by improving content distribution in a network with content name. In NDN, content is sent/received based on its name rather than its address.
Al-qutwani Majed, Xingwei Wang, Bo Yi
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Realization of Blockchain in Named Data Networking-Based Internet-of-Vehicles [PDF]
, 2019 The revolution of Internet-of-vehicles (IoV) has stimulated a substantial response from academia, research, and industry due to its massive potential to improve overall transportation.
Kurugollu, Fatih +4 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
ProNDN: MCDM-Based Interest Forwarding and Cooperative Data Caching for Named Data Networking
Journal of Computer Networks and Communications, 2021 Named data networking (NDN), as a specific architecture design of information-centric networking (ICN), has quickly became a promising candidate for future Internet architecture, where communications are driven by data names instead of IP addresses.
Cong Pu
doaj +1 more source
NCache: Neighborhood Cooperative Caching in Named Data Networking
, 2022 Improved response time and resilience to network failures are heavily influenced by the routing and caching design strategies in content centric networking. In-network caching improves response time in the network.
Kulkarni, Sameer G. +2 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source