Results 221 to 230 of about 254,529 (285)

Transformer-based relation extraction and concept normalization using an annotated clinical trials corpus. [PDF]

Sci Data
Campillos-Llanos L, Valverde-Mateos A, Capllonch-Carrión A, González-Quevedo D, López-Urbán MR, Hernando-Tundidor MS, Zakhir-Puig S, Heras J.   +7 more
europepmc   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

Chemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke, Carmelo Di Primo, Felix Bernhardt, Alea Schröder, Christian Renzl, Günter Mayer   +5 more
wiley   +1 more source

Exploring Named Entity Recognition Potential and the Value of Tailored Natural Language Processing Pipelines for Radiology, Pathology, and Progress Notes in Clinical Decision Support: Quantitative Study. [PDF]

JMIR AI
Kocaman V, Cheng FY, Bonis J, Raut G, Timsina P, Talby D, Kia A.   +6 more
europepmc   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Flat-Lattice-CNN: A model for Chinese medical-named-entity recognition. [PDF]

PLoS One
Wang S, Zhang K, Liu A.
europepmc   +1 more source

How to ‘survive’ after graduating in science or engineering: Becoming an academic administrator

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract This is the eighth article in the series ‘Survival Skills for Scientists’; previous papers were published in the Journal of Materials Education. Here I describe my views, based partly on personal experience, about pursuing an alternative career path within academia: becoming an administrator (e.g., Department Chair, Dean, Vice‐President ...
Federico Rosei
wiley   +1 more source

Nested named entity recognition in traditional Chinese medicine electronic medical records via dual-granularity feature augmentation and span classification. [PDF]

Sci Rep
Minghao L, Qing Y, Chunlei C, Peng L.
europepmc   +1 more source

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Optimized BERT-based NLP outperforms zero-shot methods for automated symptom detection in clinical practice. [PDF]

Front Digit Health
Diaz Ochoa JG, Layer N, Mahr J, Mustafa FE, Menzel CU, Müller M, Schilling T, Illerhaus G, Knott M, Krohn A.   +9 more
europepmc   +1 more source