Results 221 to 230 of about 316,674 (279)

Evaluation of SURUS: a named entity recognition NLP system to extract knowledge from interventional study records. [PDF]

open access: yesBMC Med Res Methodol
Peeters C   +5 more
europepmc   +1 more source

Machine Learning Paradigm for Advanced Battery Electrolyte Development

open access: yesCarbon Energy, EarlyView.
Electrolyte materials determine ion transport kinetics within the bulk and interphases, ultimately influencing the performance of battery systems. As data‐driven paradigms increasingly reshape materials discovery, this review provides an application‐oriented exploration of the intersection between machine learning and electrolyte science. By evaluating
Chang Su   +4 more
wiley   +1 more source

Dynamic taxonomy generation for future skills identification using a named entity recognition and relation extraction pipeline. [PDF]

open access: yesFront Artif Intell
Gonzalez-Gomez LJ   +6 more
europepmc   +1 more source

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

open access: yesChemistry – A European Journal, EarlyView.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel   +5 more
wiley   +1 more source

Morphological Control of Aurophilic Chains of Gold(I) Dithiolate Dimers With Alkali and Alkali Earth Cations

open access: yesChemistry – A European Journal, EarlyView.
Luminescent coordination polymers of Group 1 (Li, K, Cs) and 2 (Mg─Ba) cations with gold(I) iso‐maleonitriledithiolate ({Au2[S2C = C(CN)2]}2−) units were prepared; 1‐D aurophilic chains are present in all cases. The structures strongly depend on cation charge and size, with N‐cyano coordination observed in the Gp 1 and larger Gp 2 cations. Increasingly
Jefferson A. Pells   +2 more
wiley   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

open access: yesChemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke   +5 more
wiley   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

open access: yesChemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar   +13 more
wiley   +1 more source

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