Results 271 to 280 of about 554,031 (298)

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

Advanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui, Jingwei Wang, Xiaoyun Li, Lina Wang, Xuehan Mao, Rui Lyv, Wenqiang Yan, Jingyu Xu, Jieqiong Zhou, Chenxing Du, Shuhui Deng, Mu Hao, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Xin Gao, Lugui Qiu, Gang An   +18 more
wiley   +1 more source

Information flow optimization for adaptive neighbor selection graph embedding. [PDF]

Sci Rep
Wu Y, Wen X, Chen W, Mu Y.
europepmc   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs. [PDF]

BMC Med Inform Decis Mak
Kushida T, de Farias TM, Sima AC, Dessimoz C, Chiba H, Bastian FB, Masuya H.   +6 more
europepmc   +1 more source

Graph convolution network based on meta-paths and mutual information for drug-target interaction prediction. [PDF]

BMC Bioinformatics
Cao S, Cai B, Qiu Z, Chang T, Wuyun Q, Wu FX.   +5 more
europepmc   +1 more source

MVSO-PPIS: a structured objective learning model for protein-protein interaction sites prediction via multi-view graph information integration. [PDF]

Bioinformatics
Wang S, Ma T, Dong K, Han P, Li X, Ma J, Li M, Song T.   +7 more
europepmc   +1 more source

Magnetic Resonance Imaging, Fluorescence, and Drug Release Properties of Curcumin-Loaded PEGylated Magnetite@Graphene Quantum Dots Nanocomposite. [PDF]

J Biomed Phys Eng
Divband B, Al-Yasiri AY, Saeed NM, Khezerloo D, Gharehaghaji N.   +4 more
europepmc   +1 more source

A curation system of rice trait ontology with reliable interoperation by LLM and PubAnnotation. [PDF]

Genomics Inform
Ahmad JM, Liu Y, Kim JD, Yao X, Larmande P, Xia J.   +5 more
europepmc   +1 more source

Uncovering common transcriptional features shared by mature peripheral blood PMN-MDSCs and tumor-infiltrating neutrophils in humans. [PDF]

Oncoimmunology
Lattanzi C, Bianchetto-Aguilera F, Donini M, Pettinella F, Caveggion E, Castellucci M, Gasperini S, Mariotti B, Signoretto I, Cantini M, Pilotto S, Belluomini L, Tecchio C, Bazzoni F, Brandau S, Tamassia N, Cassatella MA, Scapini P.   +17 more
europepmc   +1 more source

PlantScience.ai: An LLM-Powered Virtual Scientist for Plant Science

Yu H, Zhou S, Huang M, Ding L, Chen Y, Wang Y, Ren Y, Cheng N, Wang X, Liang J, The John Innes Centre and The Sainsbury Laboratory Collaboration, Zhang H, Ding Y, Li K.   +13 more
europepmc   +1 more source