Results 331 to 340 of about 3,002,087 (370)

GraphPhos: Predict Protein-Phosphorylation Sites Based on Graph Neural Networks. [PDF]

Int J Mol Sci
Wang Z, Yang X, Gao S, Liang Y, Shi X.
europepmc   +1 more source

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

Advanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li, Fang Ye, Yucheng Zheng, Jie Wang, Haoran Peng, Lili Zhu, Lili Chen, Tao Yu, Huan Ge, Jiaqi He, Binghao Zhang, Jiayun Wu, Zhiyi Zhang, Liangliang Jiang, Geng Chen, Ping Zhao, Ke Lan, Zhenjiang Zhao, Xuhong Qian, Ke Xu, Yang Du, Honglin Li   +21 more
wiley   +1 more source

Rigorous treatment of polytopal rearrangements reveal surprising complexity of stereoisomerism configuration landscapes. [PDF]

Chem Sci
Canfield PJ, Crossley MJ.
europepmc   +1 more source

Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis

Advanced Science, EarlyView.
Salt stress endangers coastal cereal crops, requiring resilient crop solutions. This study employs machine learning (KANMB) to analyze multi‐omics data from halophyte Spartina alterniflora, revealing 226 salt‐stress biomarkers and linking them to tolerance pathways. The MYB gene SaMYB35 regulates flavonoid biosynthesis under salinity.
Shoukun Chen, Hao Zhang, Shuqiang Gao, Kunhui He, Tingxi Yu, Shang Gao, Jiankang Wang, Huihui Li   +7 more
wiley   +1 more source

HSSPPI: hierarchical and spatial-sequential modeling for PPIs prediction. [PDF]

Brief Bioinform
Li Y, Tian Z, Nan X, Zhang S, Zhou Q, Lu S.   +5 more
europepmc   +1 more source

An Improved Knowledge Graph Representation for Ransomware Attacks Using LSTM-Based Named Entity Relation Technique and Twitter Data

Khalid Jameel Munshid
openalex   +2 more sources

An Online Multimodal Food Data Exploration Platform for Specific Population Health: Development Study. [PDF]

JMIR Form Res
Yang L, Guo Z, Xu X, Kang H, Lai J, Li J.   +5 more
europepmc   +1 more source

Fusing temporal and structural information via subgraph sampling and multi-head attention for information cascade prediction. [PDF]

Sci Rep
Wang J, Li J, Liu C, Peng Y, Li X.
europepmc   +1 more source

Optimizing nanopore adaptive sampling for pneumococcal serotype surveillance in complex samples using the graph-based GNASTy algorithm. [PDF]

Genome Res
Horsfield ST, Fok BCT, Fu Y, Turner P, Lees JA, Croucher NJ.   +5 more
europepmc   +1 more source

Liquidity index of the Lublin loess as a function of cone resistance q_c from CPTU test. [PDF]

Sci Rep
Nepelski K, Lal A, Krzysiak M, Skrzypczak I, Ochab P, Gosk W.   +5 more
europepmc   +1 more source