Results 61 to 70 of about 554,031 (298)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The min-max edge q-coloring problem [PDF]
, 2013 In this paper we introduce and study a new problem named \emph{min-max edge $q$-coloring} which is motivated by applications in wireless mesh networks. The input of the problem consists of an undirected graph and an integer $q$.
Larjomaa, Tommi, Popa, Alexandru
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Generating facets for the cut polytope of a graph by triangular elimination [PDF]
, 2006 The cut polytope of a graph arises in many fields. Although much is known about facets of the cut polytope of the complete graph, very little is known for general graphs. The study of Bell inequalities in quantum information science requires knowledge of
Avis, David +2 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Key technologies and research progress of medical knowledge graph construction
大数据, 2021 With the continuous iterative updating of Internet technology, the semantic understanding of massive data is becoming more and more important.Knowledge graph is a kind of semantic network that reveals the relationship between entities.Medicine is one of ...
Ling TAN +10 more
doaj
NiceTag Ontology: tags as named graphs
, 2009 Current tag modelling does not fully take into account the rich and diverse nature tags, as signs, can take on. We propose an ontology of tags in which tags are modelled as named graphs. These named graphs are made of a resource linked to a "sign" which can be any resource reachable on the Web (an ontology concept, an image, etc.).
Limpens, Freddy +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
A named entity recognition model embedding rehabilitation medicine Chinese character knowledge graph [PDF]
PeerJ Computer ScienceBackground Named entity recognition (NER) is pivotal for medical information extraction and clinical decision support. However, most studies on Chinese medicine NER account for single-feature and multi-feature embeddings of Chinese characters, neglecting
Jinhong Zhong +5 more
doaj +2 more sources
Chinese Few-Shot Named Entity Recognition and Knowledge Graph Construction in Managed Pressure Drilling Domain [PDF]
, 2023 Siqing Wei +5 more
openalex +1 more source