Results 61 to 70 of about 682,627 (261)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Lexico-Semantic Study of the Names of the Original Districts of Akumaƒə, a Strain of the Waci Community [PDF]
This study presents the names of the original districts of Akumaƒǝ. It aims to highlight the part of linguistics sometimes neglected in the process from names to places. It is based on the lexicosemantic approach which relates to lexicology, precisely to
Edah Gaméfio Géorges Kognanou +1 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Images of the Pleiades of the Turkic and Mongolic Peoples
Introduction. The Pleiades star cluster (hereinafter referred to as a constellation) was of extreme importance in the lives of the nomads of Inner and Central Asia of all the astral objects visible in the night sky.
Marina M. Sodnompilova, Bair Z. Nanzatov
doaj +1 more source
Prilog proučavanju porijekla stanovništva i antroponimije Orahovca (Boka kotorska)
The first mention of Orahovac in the archival documents dates from the end of the fourteenth century although the name of Darantum, larger area of which Orahovac was formerly part, may be traced even earlier.
Miloš Krivokapić, Saša Knežević
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

