Results 111 to 120 of about 7,734 (200)

Modelling the regulatory toxicology system to promote the effective use of new approach methodologies: a system thinking approach. [PDF]

NAM J
Bearth A, Kopainsky B, Jones LB, Vist GE, Husøy T, Svendsen C, Whaley P, Hoffmann S, Ames HMR, Bloch D, Čavoški A, Davies HG, Giusti A, Hartung T, Kwon S, Osborne OJ, Rousselle C, Sass JB, Simanainen U, Thayer KA, Wikoff D, Mathisen GH.   +21 more
europepmc   +1 more source

From application-first to science-first: A two-phase validation framework for complex in vitro NAMs. [PDF]

Clin Pharmacol Ther
Zhu Y, Locke PA.
europepmc   +1 more source

Preparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMs. [PDF]

NAM J
Mathisen GH, Whaley P, Kopainsky B, Ames HM, Hoffmann S, Husøy T, Jones LB, Svendsen C, Vist GE, Bloch D, Cavoski A, Chiu WA, Davies HG, Giusti A, Hartung T, Hogberg HT, Kwon S, Osborne OJ, Rooney AA, Rousselle C, Sass JB, Simanainen U, Thayer KA, Wikoff D, Bearth A.   +24 more
europepmc   +1 more source

Independent testing infrastructure for new approach methodologies: the UC Davis NAMs testing center. [PDF]

Front Med Technol
Lloyd KCK.
europepmc   +1 more source

Restoring comparative expertise to improve translation of animal models. [PDF]

Dis Model Mech
Lloyd KCK.
europepmc   +1 more source

Clinical trials in a dish: cardiometabolic drug development with biological and digital twins. [PDF]

J Clin Invest
Patra D, Sayed IM, Venkateshappa R, Palaniappan L, McLaughlin T, Wu JC.   +5 more
europepmc   +1 more source

All things are active … new approach methods for excipient safety. [PDF]

Front Pharmacol
Hartung T.
europepmc   +1 more source

The rise of new approach methodologies (NAMs) for environmental safety assessment of chemicals: A systematic review of the current status, challenges and strategies for broader adoption of NAMs. [PDF]

NAM J
Christou M, Georgantzopoulou A, Hultman M, Song Y, Wennberg AC, Mentzel S, Embry M, Ott A, Suzuki T, Grassi G, Roush K, Lillicrap A.   +11 more
europepmc   +1 more source

Editorial: European partnership on the assessment of risks from chemicals (PARC): continued focus on new approach methodologies (NAMs) and data gap filling. [PDF]

Front Toxicol
Beronius A, Roggen E, Svingen T.
europepmc   +1 more source

Current and emerging new approach & methodologies for skin hazard assessment. [PDF]

Toxicol Res
Shin SY, Lim KM.
europepmc   +1 more source