Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Anisotropic nanospikes on micro and nanoscale hierarchical titanium surfaces enhance early osseointegration of dental implants. [PDF]
Ohtake T +4 more
europepmc +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source
Effects of Nano-Hydroxyapatite-Coated PRF on Gingiva-Derived Mesenchymal Stem Cells: In Vitro Study. [PDF]
Gürkan İM +4 more
europepmc +1 more source
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu +12 more
wiley +1 more source
The Effects of Polystyrene Nano/Microplastics on the Conjugative Transfer of Antibiotic Resistance Genes Between Algae and Bacteria. [PDF]
Wang Y +9 more
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
Biosynthesis, characterization, and biofunctional assessment of niobium oxide nanostructures obtained using lactic acid bacteria-derived supernatants. [PDF]
Oliveira PA +9 more
europepmc +1 more source
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Potential of Nano-Gum Arabic on the Physical, Mechanical, Adhesive, Optical, and Biological Performance of Glass Ionomer Cement: A Comprehensive In Vitro Study. [PDF]
Beleidy M +4 more
europepmc +1 more source

