Results 41 to 50 of about 681,248 (303)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

MECHANISM OF SILICA NANO-PLATE FORMATION FROM LUCENTITE

Surface Review and Letters, 2007
The mechanism of formation of silica nano-plates by exfoliation of a phyllosilicate magnesium containing clay, Lucentite, in an aqueous solution of poly(acrylic acid) has been studied. Fourier transform infrared spectroscopy and Mg K -edge near edge X-ray adsorption fine structure (NEXAFS) analysis shows that non-surface (bulk) Mg ions were not ...
Tran, Nguyen H., Wilson, Michael A., Milev, Adriyan S., Dennis, Gary R., Kannangara, Kamali   +4 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Integrating Al with NiO nano honeycomb to realize an energetic material on silicon substrate [PDF]

, 2009
Nano energetic materials offer improved performance in energy release, ignition, and mechanical properties compared to their bulk or micro counterparts. In this study, the authors propose an approach to synthesize an Al/NiO based nano energetic material ...
Rossi, Carole, Tenailleau, Christophe, Cayez, Simon, Chane-Ching, Jean-Yves, Zhang, Kaili, Alphonse, Pierre   +5 more
core   +1 more source

Enhancement of the Modulation Response of Quantum-Dot-Based Down-Converted Light through Surface Plasmon Coupling

Molecules, 2022
In this paper, we first elaborate on the effects of surface plasmon (SP) coupling on the modulation responses of the emission of a light-emitting diode (LED) and its down-converted lights through colloidal quantum dots (QDs).
Shaobo Yang, Po-Yu Chen, Chia-Chun Ni, Jun-Chen Chen, Zong-Han Li, Yang Kuo, Chih-Chung Yang, Ta-Cheng Hsu, Chi-Ling Lee   +8 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Electrical Behaviour of Glass/ Carbon- Phenolic Conductive Hybrid Composite Woven Used In Electrostatics Precipitator Filter

International Journal of Electrochemical Science, 2014
Electrical behavior of hybrid conductive composites made of phenolic resin, graphite woven, glass woven and graphite nano powder has been studied for the first time in the present research to apply as collecting plates in electro static precipitators. To
A.A. Lotfi Neyestanak, S. Adib Nazari, N. Sadeghbeigi, A. Karimzadeh   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

nlesc-nano/Nano-Utils: Nano-Utils 2.3.3

, 2022
What's Changed ENH: Avoid double-loops in _RecursiveMappingView by @BvB93 in https://github.com/nlesc-nano/Nano-Utils/pull/37 Full Changelog: https://github.com/nlesc-nano/Nano-Utils/compare/2.3.2...2.3.
Bas van Beek
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source