Results 281 to 290 of about 19,829 (313)

Imaging of tumor-associated macrophage dynamics during immunotherapy using a CD163-specific nanobody-based immunotracer. [PDF]

Proc Natl Acad Sci U S A
Lauwers Y, De Groof TWM, Vincke C, Van Craenenbroeck J, Jumapili NA, Barthelmess RM, Courtoy G, Waelput W, De Pauw T, Raes G, Devoogdt N, Van Ginderachter JA.   +11 more
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Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms

Mobach S, Bergkamp ND, Ma Z, Haselager MV, Anbuhl SM, Jurriens D, Bor Jvd, Wang Z, Crudden C, Roos JL, Perez Almeria CV, Boergonje RA, Lohse MJ, Bosma R, Eldering E, Siderius M, Wu W, Spaargaren M, Tonino SH, Kater AP, Smit MJ, Heukers R.   +21 more
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Self-Assembly Multivalent Fluorescence-Nanobody Coupled Multifunctional Nanomaterial with Colorimetric Fluorescence and Photothermal to Enhance Immunochromatographic Assay.

ACS Nano, 2023
The multimodal lateral flow immunoassay (LFIA) has provided accurate and reliable results for fast and immediate detection. Nonetheless, multimodal LFIA remains challenging to develop biosensors with high sensitivity and tolerance to matrix interference ...
Zhiqiang Li, Wen Zhang, Qi Zhang, Peiwu Li, Xiaoqian Tang   +4 more
semanticscholar   +1 more source

Dual-Modal Immunosensor Made with the Multifunction Nanobody for Fluorescent/Colorimetric Sensitive Detection of Aflatoxin B1 in Maize.

ACS Applied Materials and Interfaces, 2023
In recent years, dual-modal immunosensors based on synthetic nanomaterials have provided accurate and sensitive detection. However, preparation of nanomaterial probes can be time-consuming, laborious, and not limited to producing inactive and low ...
Jiasi Zuo, Tingting Yan, Xiaoqian Tang, Qi Zhang, Peiwu Li   +4 more
semanticscholar   +1 more source

Additive efficacy of a bispecific anti–TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis

Science Translational Medicine, 2023
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases affecting primarily the joints. Despite successful therapies including antibodies against tumor necrosis factor (TNF) and interleukin-6 (IL-6) receptor, only 20 to 30% of patients ...
Nadine Biesemann, D. Margerie, C. Asbrand, Markus Rehberg, Virginia Savova, I. Agueusop, Daniel Klemmer, D. Ding-Pfennigdorff, U. Schwahn, Markus Dudek, K. Heyninck, Evelyn De Tavernier, S. Cornelis, M. Kohlmann, F. Nestle, M. Herrmann   +15 more
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Multivalent Nanobody Conjugate with Rigid, Reactive Oxygen Species Scavenging Scaffold for Multi‐Target Therapy of Alzheimer's Disease

Advances in Materials, 2023
Efficient therapeutic strategies that concurrently target both Aβ aggregation and oxidative stress in the Alzheimer's disease (AD) microenvironment emerge as a cutting‐edge tool to combat the intricate pathogenesis of AD.
Liyuan Zhao, Fanling Meng, Yingjie Li, Sujuan Liu, Mengmeng Xu, F. Chu, Chuanzhou Li, Xiangliang Yang, Liang Luo   +8 more
semanticscholar   +1 more source