Results 41 to 50 of about 12,245 (209)

Micro- and nano bio-based delivery systems for food applications: In vitro behavior [PDF]

, 2017
Micro- and nanoencapsulation is an emerging technology in the food field that potentially allows the improvement of food quality and human health. Bio-based delivery systems of bioactive compounds have a wide variety of morphologies that influence their ...
Madalena, Daniel A., Pinheiro, Ana Cristina, Ramos, Óscar L., Simões, Lívia Souza, Teixeira, J. A., Vicente, A. A.   +5 more
core   +1 more source

A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms

Food Innovation and Advances, 2023
Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao, Talha Ahmad, Tarun Belwal, Rana Muhammad Aadil, Muhammad Siddique, Limin Pang, Yanqun Xu   +6 more
doaj   +1 more source

Poly(D,L-lactic-co-glycolic acid) nanoencapsulation reduces erlotinib-Induced subacute toxicity in rat [PDF]

, 2009
Erlotinib-HCl is a quinazoline derivative used as a drug in the therapy of non-small-cell lung cancer. The present study was conducted to compare the subacute toxicity induced by Erlotinib-HCl delivered to rats as nanoparticles and as free drug. Wistar
Gregory, Franklin, Gregory, Marslin, Kalaichelvan, V. K., Manavalan, R., Reddy, Neelakanta, Sheeba, Caroline J.   +5 more
core   +1 more source

Single Step Double-walled Nanoencapsulation (SSDN) [PDF]

Journal of Controlled Release, 2018
A quick fabrication method for making double-walled (DW) polymeric nanospheres is presented. The process uses sequential precipitation of two polymers. By choosing an appropriate solvent and non-solvent polymer pair, and engineering two sequential phase inversions which induces first precipitation of the core polymer followed by precipitation of the ...
Aharon, Azagury, Vera C, Fonseca, Daniel Y, Cho, James, Perez-Rogers, Christopher M, Baker, Elaine, Steranka, Victoria, Goldenshtein, Dominick, Calvao, Eric M, Darling, Edith, Mathiowitz   +9 more
openaire   +2 more sources

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Nanoemulsion and nanoencapsulation of a hydroethanolic extract of Nettle (Urtica dioica) and Wormwood (Artemisia absinthium): comparison of antibacterial and anticancer activity

Frontiers in Chemistry
Introduction: Nanoemulsion and nanoencapsulation are attractive novel methods that can be used for incorporating active plant extracts in food preparations and pharmaceutical formulations.
Zeinab Rahmani, Merat Karimi, Iman Saffari, Hamed Mirzaei, Majid Nejati, Reza Sharafati Chaleshtori   +5 more
doaj   +1 more source

Bacterial-derived Polymer Poly-y-Glutamic Acid (y-PGA)-based micro/nanoparticles as a delivery system for antimicrobials and other biomedical applications [PDF]

, 2017
: In the past decade, poly-γ-glutamic acid (γ-PGA)-based micro/nanoparticles have garnered remarkable attention as antimicrobial agents and for drug delivery, owing to their controlled and sustained-release properties, low toxicity, as well as ...
Adamus, Grazyna, Burns, Alan, Johnston, Brian, Khalaf, Tamara, Khalil, Ibrahim, Khechara, Martin, Kowalczuk, Marek, Radecka, Iza   +7 more
core   +2 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Optimizing the ultrasonic extraction of polyphenols from mango peel and investigating the characteristics, antioxidant activity and storage stability of extract nanocapsules in maltodextrin/whey protein isolate

Ultrasonics Sonochemistry
In this study, the extraction and nanoencapsulation of mango peel extract (MPE) were investigated to enhance its stability and preserve its antioxidant properties.
Shahram Saborirad, Homa Baghaei, Hamid Hashemi-Moghaddam   +2 more
doaj   +1 more source