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Biomedical applications of nanoflares: Targeted intracellular fluorescence probes. [PDF]

open access: greenNanomedicine, 2019
Nanoflares are intracellular probes consisting of oligonucleotides immobilized on various nanoparticles that can recognize intracellular nucleic acids or other analytes, thus releasing a fluorescent reporter dye. Single-stranded DNA (ssDNA) complementary to mRNA for a target gene is constructed containing a 3'-thiol for binding to gold nanoparticles ...
Chenab KK   +5 more
europepmc   +7 more sources

Photocaged amplified FRET nanoflares: spatiotemporal controllable of mRNA-powered nanomachines for precise and sensitive microRNA imaging in live cells. [PDF]

open access: goldNucleic Acids Res, 2022
There is considerable interest in creating a precise and sensitive strategy for in situ visualizing and profiling intracellular miRNA. Present here is a novel photocaged amplified FRET nanoflare (PAFN), which spatiotemporal controls of mRNA-powered ...
Li J   +6 more
europepmc   +4 more sources

Self-Consistent Heating of the Magnetically Closed Solar Corona: Generation of Nanoflares, Thermodynamic Response of the Plasma and Observational Signatures

open access: goldThe Astrophysical Journal
The energy that heats the magnetically closed solar corona originates in the complex motions of the massive photosphere. Turbulent photospheric convection slowly displaces the footpoints of coronal field lines, causing them to become twisted and tangled.
Craig D. Johnston   +7 more
doaj   +3 more sources

Measurement of energy distribution for low power nanoflares

open access: yesSolar-Terrestrial Physics, 2023
We propose a method to measure the energy distribution of low-energy flares (nanoflares) in the energy range below 1023 erg. As an example, we measured the spectrum of nanoflares in the 1021–1026 erg range for two Sun’s frames observed by the SDO/AIA ...
Bogachev S.A., Erkhova N. F.
doaj   +2 more sources

A Statistical Study of IRIS Observational Signatures of Nanoflares and Nonthermal Particles [PDF]

open access: yesThe Astrophysical Journal, 2023
Nanoflares are regarded as one of the major mechanisms of magnetic energy release and coronal heating in the solar outer atmosphere. We conduct a statistical study on the response of the chromosphere and transition region to nanoflares, as observed by ...
Kyuhyoun Cho   +3 more
doaj   +2 more sources

Statistical Properties of Synthetic Nanoflares [PDF]

open access: bronzeThe Astrophysical Journal, 2006
Statistical properties of flares are a powerful tool for addressing the upper solar atmosphere heating problem. We simulate time series of synthetic flares by means of a dynamic model of the atmospheric magnetic field in which magnetic loop footpoints are controlled by photospheric flows computed through a n-body algorithm.
Viticchie, B   +2 more
openaire   +4 more sources

OBSERVING CORONAL NANOFLARES IN ACTIVE REGION MOSS [PDF]

open access: bronzeThe Astrophysical Journal, 2013
Accepted for publication on The Astrophysical Journal Letters. 5 figures. Movies can be found at: http://www.lmsal.com/~ptesta/hic_moss/
Testa, Paola   +14 more
openaire   +4 more sources

Gene Regulation Using Spherical Nucleic Acids to Treat Skin Disorders [PDF]

open access: yesPharmaceuticals, 2020
Spherical nucleic acids (SNAs) are nanostructures consisting of nucleic acids in a spherical configuration, often around a nanoparticle core. SNAs are advantageous as gene-regulating agents compared to conventional gene therapy owing to their low ...
Thomas R. Holmes, Amy S. Paller
doaj   +2 more sources

Differential emission measure of solar nanoflares measured with the SITES algorithm

open access: yesSolar-Terrestrial Physics
The paper presents the results of a study of capabilities of the SITES algorithm for reconstructing the differential emission measure (DEM) of a source from its radiation in several parts of the electromagnetic spectrum in the context of observing solar ...
Belov S. A.   +3 more
doaj   +2 more sources

Thermophoretic Detection of Exosomal microRNAs by NanoFlares.

open access: yesJournal of the American Chemical Society, 2020
Exosomal microRNAs (miRNAs) are reliable and non-invasive biomarkers for the early diagnosis of cancer. Yet, accurate and feasible detection of exosomal miRNAs is often hampered by the low abundance of miRNAs in exosomes and the requirement for RNA ...
Junxiang Zhao   +6 more
semanticscholar   +3 more sources

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