Results 181 to 190 of about 1,370 (209)

Nanoflares as Probes for Cancer Diagnostics

2015
Patients whose cancer is detected early are much more likely to have a positive prognosis and outcome. Nanoflares hold promise as a practical diagnostic platform for the early detection of cancer markers in living cells. These probes are based on spherical nucleic acid (SNAs) and are typically composed of gold nanoparticle cores and densely packed and ...
Pratik S, Randeria, William E, Briley, Alyssa B, Chinen, Chenxia M, Guan, Sarah Hurst, Petrosko, Chad A, Mirkin   +5 more
openaire   +2 more sources

A DNA Tetrahedron Assembly-Based Nanoshell-Mediated Nanoflares for Intracellular MiRNA Imaging: Reducing False Positivity and Improving Reaction Kinetics and Efficiency.

Analytical Chemistry
Nanoflares (NFs) are extensively used for the analysis of biomarkers within living cells. However, the severe false positives and low reaction efficiency and kinetics have restricted the further application of NF.
Zi-Chuan Yang, Qianying Zhou, Mengxu Sun, Simin Liu, Jing Peng, Ting Huang, Chunrong Li, Yanfei Zhang, Yinxia Liu, Wenjun Duan, Zong Dai, Jinxiang Chen, Jun Chen   +12 more
semanticscholar   +1 more source

Engineering Inorganic Nanoflares with Elaborate Enzymatic Specificity and Efficiency for Versatile Biofilm Eradication.

Small, 2020
Nanozyme has emerged as a versatile nanocatalyst yet is constrained with limited catalytic efficiency and specificity for various biomedical applications.
Meijuan Liang, Yanbing Wang, Kang Ma, Shanshan Yu, Yingying Chen, Zhao Deng, Yi Liu, Fuan Wang   +7 more
semanticscholar   +1 more source

Power-Law Nanoflare Heating

2009
Nanoflares are small impulsive events in the corona that dissipate magnetic energy in the range 5 × 1023 to 1026 ergs. We model their characteristics through assuming a power-law event distribution.
L. Prasad, V. K. Joshi
openaire   +1 more source

Physically Masked Nanoflares for Accurate Biological Applications by Blocking Nucleases.

Angewandte Chemie
Nanoflare integrated with a gold nanoparticle (Au NP) core and a functional oligonucleotide shell is a powerful platform for bio-applications, such as sensing, imaging, diagnosis, and therapy. However, degradation of nucleic acids by endogenous nucleases
Yibo Zhou, Yuping Wang, Aoshuang Xu, Qiuhong Mo, Xiaowen Liu, Min Liu, Xiaohan Zhang, Juewen Liu, Zhihe Qing   +8 more
semanticscholar   +1 more source

Single-Nucleotide-Specific Lipidic Nanoflares for Precise and Visible Detection of KRAS Mutations via Toehold-Initiated Self-Priming DNA Polymerization.

Analytical Chemistry
Accurate identification of single-nucleotide mutations in circulating tumor DNA (ctDNA) is critical for cancer surveillance and cell biology research.
Chan Li, Haiyan Jia, Xiaoling Wei, Guohui Xue, Jianguo Xu, Ruize Cheng, Ying-Sheng Cheng, Qiufeng Song, Zhifa Shen, Chang Xue   +9 more
semanticscholar   +1 more source

Gold Nanoflares with Computing Function as Smart Diagnostic Automata for Multi-miRNA Patterns in Living Cells.

Analytical Chemistry, 2020
Investigating the multimolecule patterns in living cells is of vital importance for clinical and biomedical studies. Herein, we reported for the first time the engineering of gold nanoflares as smart automata to implement computing-based diagnosis in ...
Lan Liu, Na Li, Zhimei Huang, Li-Juan Tang, Zhan‐Ming Ying, Jian-hui Jiang   +5 more
semanticscholar   +1 more source

Well-defined DNA-Polymer Miktoarm Stars for Enzyme-Resistant Nanoflares and Carrier-Free Gene Regulation.

Bioconjugate chemistry, 2020
Herein, we report a star-architectured poly(ethylene glycol) (PEG)-oligonucleotide nanoconjugate of a well-defined molecular structure. Based upon fullerene C60 cores, each star bears precisely one DNA strand and eleven polymer chains.
Hui Li, Yang Li, Yue Xiao, Zehong Cheng, Jianqiao Shi, Bohan Zhang, Jing Xiong, Zhaohui Li, Kecheng Zhang   +8 more
semanticscholar   +1 more source

Universal Nanoflares

1994
Abstract The basic theorem of magnetostatics asserts that the Maxwell stresses 111 all but the simplest field topologies continually strive to produce current sheets of vanishing thickness and unbounded current density, i.e., surfaces of tangential discontinuity in the magnetic field. In astronomical settings the small resistivity of the
openaire   +1 more source

Photoactivated Nanoflares for mRNA Detection in Single Living Cells.

Analytical Chemistry, 2019
Gold nanoparticles (AuNPs) have shown great promise as a universal platform for biosensing and are often functionalized with a densely packed DNA for intracellular detection.
Meihua Lin, Xiaoqing Yi, Fujian Huang, Xin Ma, Xiaolei Zuo, Fan Xia   +5 more
semanticscholar   +1 more source